Lung imaging is increasingly being used to diagnose, quantify, and phenotype chronic
obstructive pulmonary disease (COPD). Although spirometry is the gold standard for the …

OBJECTIVE. The purpose of this study was to determine whether the predominant findings
at high-resolution CT influence the accuracy of diagnosis of diffuse lung disease …

Context Smoking is a major risk factor for both cancer and chronic obstructive pulmonary
disease (COPD). Computed tomography (CT)–based lung cancer screening may provide an …

T he introduction of computed tomography (CT) of the chest has undoubtedly provided
clinicians with a new and valuable diagnostic tool. Compared with plain chest radiography …

Measurements of lung function, including spirometry and body plethesmography, are easy
to perform and are the current clinical standard for assessing disease severity. However …

OBJECTIVE. The purpose of the present study is to prospectively compare the capability of
dynamic oxygen-enhanced MRI and quantitative CT for pulmonary functional loss …

Rationale and Objectives Previous investigation suggests that visually detected interstitial
changes in the lung parenchyma of smokers are highly clinically relevant and predict …

Purpose To evaluate the prevalence and significance of the pathological effects of cigarette
smoking on the lung and the sensitivity of high-resolution CT (HRCT) in the recognition of …

The histopathological abnormalities that characterize cigarette smokers' lung damage have
been widely studied, but these microscopic changes do not fully explain the radiographic …

To evaluate the ability of high-resolution computed tomography (HRCT) to detect
longitudinal changes in structural abnormalities caused by smoking, HRCT and pulmonary …