Background/Aims: Cardiac remodeling is a common pathophysiological change along with
chronic hypertension and myocardial infarction. Recent evidence indicated that cardiac …

Aims Peroxisome proliferator-activated receptor-α (PPARα) is a nuclear receptor regulating
cardiac metabolism that also has anti-inflammatory properties. Since the activation of …

Objectives Pharmacological activation of peroxisome proliferator-activated receptor gamma
(PPARγ) has been shown to attenuate pressure overload-induced cardiac fibrosis …

Peroxisome proliferator activated receptor γ (PPARγ) has been closely involved in the
process of cardiovascular diseases. This study was to investigate whether pioglitazone …

Peroxisome proliferator-activated receptor α (PPARα), a ligand-activated nuclear receptor
critical for systemic lipid homeostasis, has been shown closely related to cardiac …

Background Peroxisome proliferator-activated receptors (PPARs) are transcription factors
belonging to the nuclear receptor superfamily. PPARγ mRNA is present in cardiac myocytes; …

Diabetic cardiomyopathy (DCM) is a kind of disease caused by metabolic disorders and
microangiopathy. The main pathophysiological changes of DCM include fibrosis, myocardial …

Background.–Peroxisome proliferator-activated receptor (PPAR) α is highly expressed in the
heart. PPARα may play a role in cardiac hypertrophy, but effects on cardiac function …

Although peroxisome proliferator‐activated receptor α (PPARα) is highly expressed in the
heart, the effects of PPARα on cardiac remodelling and the underlying mechanisms are …

Peroxisome proliferator-activated receptor-gamma (PPARγ) is one of the hormone nuclear
receptors. Recent data have shown that activation of PPARγ signal pathway has many …