Background Diabetic cardiomyopathy is characterized by both systolic and diastolic
dysfunction due to decreased contractility, as well as reduced compliance of the …

Aim This study aimed to investigate the therapeutic effects of salidroside on diabetes‐
induced cardiovascular disease. Methods Sprague–Dawley rats treated with 65 mg/kg of …

To investigate the effects and the underlying mechanisms of salidroside on diabetic
cardiomyopathy, diabetes was induced in mice by a long‐term high‐fat diet and a low‐dose …

In the present study, we investigated cardioprotective effects of salidroside, isolated from
Rhodiola rosea L, on oxygen–glucose deprivation (OGD)-induced cardiomyocyte death and …

Background Hyperglycemia-induced cardiovascular dysfunction has been linked to
oxidative stress and accelerated apoptosis in the diabetic myocardium. While there is …

Cardiomyocyte death (necrosis and apoptosis) plays a critical role in the progress of heart
diseases. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea L, has …

Aim: The enhanced oxidative stress contributes to progression of type 2 diabetes mellitus
(T2DM) and induces β-cell failure. Salidroside is a natural antioxidant extracted from …

Background Type 2 diabetes mellitus increases the risk of cardiovascular disease including
myocardial infarction (MI). Inflammation and apoptosis have been implicated in the …

The mitochondria are highly dynamic organelles, carefully maintaining network homeostasis
by regulating mitochondrial fusion and fission. Mitochondrial dynamics are involved in the …

Background Inflammation and oxidative stress play essential roles in the occurrence and
progression of diabetic cardiomyopathy (DCM). Isoliquiritigenin (ISL), a natural chalcone …