Immune regulation of metabolic homeostasis in health and disease
JR Brestoff, D Artis - Cell, 2015 - cell.com
Obesity is an increasingly prevalent disease worldwide. While genetic and environmental
factors are known to regulate the development of obesity and associated metabolic …
factors are known to regulate the development of obesity and associated metabolic …
Innate immune control of adipose tissue homeostasis
Adipose tissue is a critical regulator of systemic metabolism and normal bodily homeostasis.
Recently, the immune system has been implicated in the regulation of adipose tissue …
Recently, the immune system has been implicated in the regulation of adipose tissue …
Resident and migratory adipose immune cells control systemic metabolism and thermogenesis
Glucose is a vital source of energy for all mammals. The balance between glucose uptake,
metabolism and storage determines the energy status of an individual, and perturbations in …
metabolism and storage determines the energy status of an individual, and perturbations in …
[HTML][HTML] Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity
Recent findings, notably on adipokines and adipose tissue inflammation, have revised the
concept of adipose tissues being a mere storage depot for body energy. Instead, adipose …
concept of adipose tissues being a mere storage depot for body energy. Instead, adipose …
Interplay between the immune system and adipose tissue in obesity
Obesity is a major risk factor for metabolic disease, with white adipose tissue (WAT)
inflammation emerging as a key underlying pathology. Alongside its major role in energy …
inflammation emerging as a key underlying pathology. Alongside its major role in energy …
Adipose tissue immunomodulation: a novel therapeutic approach in cardiovascular and metabolic diseases
Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …
Adipose tissue-resident immune cells: key players in immunometabolism
HS Schipper, B Prakken, E Kalkhoven… - Trends in Endocrinology & …, 2012 - cell.com
Adipose tissue (AT) plays a pivotal role in whole-body lipid and glucose homeostasis. AT
exerts metabolic control through various immunological mechanisms that instigated a new …
exerts metabolic control through various immunological mechanisms that instigated a new …
The adaptive immune system as a fundamental regulator of adipose tissue inflammation and insulin resistance
Over the past decade, chronic inflammation in visceral adipose tissue (VAT) has gained
acceptance as a lead promoter of insulin resistance in obesity. A great deal of evidence has …
acceptance as a lead promoter of insulin resistance in obesity. A great deal of evidence has …
Adipocytes, innate immunity and obesity: A mini-review
AM Blaszczak, A Jalilvand, WA Hsueh - Frontiers in immunology, 2021 - frontiersin.org
The role of adipose tissue (AT) inflammation in obesity and its multiple related-complications
is a rapidly expanding area of scientific interest. Within the last 30 years, the role of the …
is a rapidly expanding area of scientific interest. Within the last 30 years, the role of the …
Immune regulation in obesity-associated adipose inflammation
JM Han, MK Levings - The Journal of Immunology, 2013 - journals.aai.org
Adipose tissue inflammation is often a consequence of obesity and is characterized by
infiltration and activation of immune cells that overproduce cytokines and chemokines. This …
infiltration and activation of immune cells that overproduce cytokines and chemokines. This …
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