Iron deficiency anemia can be treated with oral or intravenous Fe supplementation. Such
supplementation has considerable effects on the human microbiome, and on opportunistic …

The unique redox potential of iron makes it an ideal cofactor in diverse biochemical
reactions. Iron is therefore vital for the growth and proliferation of nearly all organisms …

Staphylococcus aureus pathogenesis is significantly influenced by the iron status of the host.
However, the regulatory impact of host iron sources on S. aureus gene expression remains …

Nutritional immunity is a form of innate immunity widespread in both vertebrates and
invertebrates. The term refers to a rich repertoire of mechanisms set up by the host to inhibit …

The acute-phase response is triggered by the presence of infectious agents and danger
signals which indicate hazards for the integrity of the mammalian body. One central feature …

Iron is an essential nutrient for both humans and pathogenic microbes. Because of its ability
to exist in one of two oxidation states, iron is an ideal redox catalyst for diverse cellular …

Iron is an essential micronutrient for nearly all living organisms. In addition to facilitating
redox reactions, iron is bound by metalloproteins that participate in a variety of biological …

Iron holds a central position at the host–pathogen interface because mammalian and
microbial cells have an essential demand for the metal, which is required for many metabolic …

Iron plays a crucial role in the biochemistry and development of nearly all living organisms.
Iron starvation of pathogens during infection is a striking feature utilized by a host to quell …

Highlights•Staphylopine is a metallophore that Staphylococcus aureus deploys to acquire
first-row transition metals.•The protein SbnI provides a link between heme uptake and …