Omics in Precision Medicine

O Kayalar, H Rajabi, D Mortazavi, H Bayram - … , Precision Medicine and …, 2023 - Springer
Cancer is a multifaceted and complex disease that results from the disruption of genetic,
epigenetic, and metabolic systems responsible for maintaining physiological conditions in …

[HTML][HTML] Omics and therapy–a basis for precision medicine

JP Garay, JW Gray - Molecular oncology, 2012 - Elsevier
A founding premise of the human genome project was that knowledge of the spectrum of
abnormalities that comprise cancers and other human diseases would lead to improved …

The need for multi-omics biomarker signatures in precision medicine

M Olivier, R Asmis, GA Hawkins, TD Howard… - International journal of …, 2019 - mdpi.com
Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …

Why do cancer Omics attract clinicians so much?

L Massimo, MV Corrias, GP Tonini - OMICS: A Journal of Integrative …, 2011 - go.gale.com
Since its first steps, Clinical Oncology has looked to basic research in the hope of fully
understanding carcinogenesis and finding a better way to cure patients. Today, to the many …

OMICs profiling of cancer cells

B Larijani, P Goodarzi, M Sheikh Hosseini… - … and Metabolomics: Stem …, 2019 - Springer
The number of people survive from cancer is increasing in the USA due to the advances in
the early detection and treatment. Cancer is a complex disease caused by several factors …

Towards Precision Oncology: Advancing Multiomic Biomarker Discovery with Mass Spectrometry Proteomics

SM Junior - 2024 - portal.research.lu.se
Over the past couple of decades, considerable advances in automation and high-throughput
omics technologies have contributed to the generation of unprecedented amounts of …

A journey from omics to clinicomics in solid cancers: Success stories and challenges.

S Mehrotra, S Sharma, RK Pandey - Advances in Protein Chemistry …, 2024 - europepmc.org
The word'cancer'encompasses a heterogenous group of distinct disease types
characterized by a spectrum of pathological features, genetic alterations and response to …

New omics information for clinical trial utility in the primary setting

G Damia, M Broggini, S Marsoni… - Journal of the …, 2011 - academic.oup.com
Cancer is a complex cellular disease caused by multiple factors via genetic mutations
(hereditary or somatic) or environmental factors. The emerging omics technologies …

Cancer biomarker discovery and translation: proteomics and beyond

VA Hristova, DW Chan - Expert review of proteomics, 2019 - Taylor & Francis
Introduction: Cancer is often diagnosed at late stages when the chance of cure is relatively
low and although research initiatives in oncology discover many potential cancer …

Precision cancer medicine: Concept, technology and perspectives

B HANG, Y SHU, P LIU, G WEI, J JIN, W HAO… - Science & Technology …, 2015 - kjdb.org
Precision medicine is defined as an approach to personalized diagnosis and treatment,
based on the omics information of patients. Human cancer is a complex and intrinsically …