[HTML][HTML] miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway

F Zhou, YK Wang, CG Zhang, BY Wu - Journal of neuroinflammation, 2021 - Springer
Abstract Background Stroke affects 3–4% of adults and kills numerous people each year.
Recovering blood flow with minimal reperfusion-induced injury is crucial. However, the …

[HTML][HTML] Inhibition of miR-19a-3p decreases cerebral ischemia/reperfusion injury by targeting IGFBP3 in vivo and in vitro

Z Chai, J Gong, P Zheng, J Zheng - Biological research, 2020 - Springer
Background Inflammation and apoptosis are considered to be two main factors affecting
ischemic brain injury and the subsequent reperfusion damage. MiR-19a-3p has been …

[HTML][HTML] Upregulation of miR-874-3p decreases cerebral ischemia/reperfusion injury by directly targeting BMF and BCL2L13

D Jiang, X Sun, S Wang, H Man - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Ischemic stroke represents a major cause of adult physical disability, which is triggered by
cerebral artery occlusion induced blood flow blockage. MiR-874-3p has been reported to be …

miR-124-5p/NOX2 axis modulates the ROS production and the inflammatory microenvironment to protect against the cerebral I/R injury

Y Wu, J Yao, K Feng - Neurochemical research, 2020 - Springer
The reperfusion after an acute ischemic stroke can lead to a secondary injury, which is
ischemia–reperfusion (I/R) injury. During ischemia, the reactive oxygen species (ROS) is …

[PDF][PDF] MiR-155-5p accelerates cerebral ischemia-reperfusion injury via targeting DUSP14 by regulating NF-κB and MAPKs signaling pathways.

Y Shi, K Li, K Xu, QH Liu - European Review for Medical & …, 2020 - europeanreview.org
OBJECTIVE: This study aimed to explore the role of miR-155-5p in middle cerebral artery
occlusion/reperfusion (MCAO/R) model in rats and oxygen-glucose deprivation …

miR-9-5p attenuates ischemic stroke through targeting ERMP1-mediated endoplasmic reticulum stress

L Chi, D Jiao, G Nan, H Yuan, J Shen, Y Gao - Acta Histochemica, 2019 - Elsevier
Ischemic stroke (IS) is a cerebrovascular disease with serious neurological function
impairment, which may activate endoplasmic reticulum (ER) stress. However, the underlying …

KCNQ1OT1 exacerbates ischemia–reperfusion injury through targeted inhibition of miR-140-3P

M Yi, Y Li, D Wang, Q Zhang, L Yang, C Yang - Inflammation, 2020 - Springer
Potassium voltage-gated channel subfamily Q member 1 opposite strand 1 (KCNQ1OT1), a
long non-coding RNA found in the KCNQ1 locus, has been evidenced to play important …

[HTML][HTML] miRNA-3473b contributes to neuroinflammation following cerebral ischemia

X Wang, S Chen, J Ni, J Cheng, J Jia, X Zhen - Cell Death & Disease, 2018 - nature.com
MicroRNAs play an essential role in stroke pathology. Here, we investigated the role of a
newly identified microRNA, miR-3473b, in stroke pathology. The expression of miR-3473b …

MiR-34b protects against focal cerebral ischemia-reperfusion (I/R) injury in rat by targeting Keap1

R Huang, J Ma, B Niu, J Li, J Chang, Y Zhang… - Journal of Stroke and …, 2019 - Elsevier
Ischemic stroke is one of the leading causes of death and disability globally and has been
regarded as a major public health problem. Understanding the mechanism of …

Up-regulation of miR-122 protects against neuronal cell death in ischemic stroke through the heat shock protein 70-dependent NF-κB pathway by targeting FOXO3

D Guo, J Ma, T Li, L Yan - Experimental cell research, 2018 - Elsevier
Dysfunction of the microRNA (miRNA) network has been emerging as a main regulator in
ischemic stroke. Recently, studies have linked the deregulation of miR-122 to ischemic …