Significance: Alzheimer disease (AD) is an age-related neurodegenerative disease. AD is
characterized by progressive cognitive impairment. One of the main histopathological …

Neurologists have highly observed a frequent increasing number of elderly patients with
Alzheimer's disease (AD) without any relevant evidence of any genetic or known AD‐linked …

Neurodegenerative diseases have great social and economic impact and cause millions of
deaths every year. The potential molecular mechanisms in these pathologies have been …

Amyloid β-peptide (Aβ) is heavily deposited in the brains of Alzheimer's disease (AD)
patients, and free radical oxidative stress, particularly of neuronal lipids and proteins, is …

Protein oxidation, one of a number of brain biomarkers of oxidative stress, is increased in
several age-related neurodegenerative disorders or animal models thereof, including …

Oxidative stress has been linked with a variety of diseases, being involved in the debut
and/or progress of several neurodegenerative disorders. This review intends to summarize …

Lipid peroxidation is a complex process involving the interaction of oxygen-derived free
radicals with polyunsaturated fatty acids, resulting in a variety of highly reactive electrophilic …

Reactive oxygen species (ROS) have been described to induce a broad range of redox-
dependent signaling reactions in physiological conditions. Nevertheless, an excessive …

Age-related neurodegenerative diseases, especially Alzheimer's disease (AD), are an
important health problem globally. AD is clinically characterized by loss of memory …

Alzheimer disease (AD), the most common dementing disorder, is a multifactorial disease
with complex etiology. Among different hypotheses proposed for AD one of the most …