Background Diatomite is a natural porous biomaterial of sedimentary origin, formed by
fragments of diatom siliceous skeletons, called “frustules”. Due to large availability in many …

Verschlossene Röhren: Das Anbinden selbstkomplementärer Duplex‐DNA an die
Öffnungen mesoporöser Siliciumoxidnanopartikel erzeugt einen Deckel zum Fixieren von …

Development of reliable vectors is a major challenge in gene therapy. Previous gene
transfer methods using non-viral vectors, such as liposomes or nanoparticles, have resulted …

In this article, a systematic study of the design and development of surface-modification
schemes for silica nanoparticles is presented. The nanoparticle surface design involves an …

An attempt was made to control the surface charge of colloidal silica nanoparticles with 20
nm and 100 nm diameters. Untreated silica nanoparticles were determined to be highly …

Cationic solid lipid nanoparticles (SLN) have recently been suggested for non-viral gene
delivery, as these particles consist of well tolerated substances, can bind DNA directly via …

Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

The nonviral gene delivery system is an attractive alternative to cancer therapy. A new kind
of gelatin-silica nanoparticles (GSNPs) was developed through a two-step sol–gel …

In this paper, the suitability of novel cationic solid-lipid nanoparticles (SLN) as a nonviral
transfection agent for gene delivery was investigated. SLN were produced by using the …

Aimed at high loading and controlled release of oligonucleotides with short sequences of
base-pairs, a novel series of mesoporous silica nanoparticles with three different pore sizes …