Haemophilus influenzae, a gram-negative rod-shaped bacterium, is a major human
pathogen that causes a range of diseases in infants, children, and adults. There are six …

Haemophilus influenzae type b (Hib) conjugate vaccines, consisting of the type b capsular
saccharide covalently linked to a protein carrier or a bacterial protein membrane complex …

Haemophilus influenzae type b (Hib) conjugate vaccines represent a new technology
wherein an immunogen is targeted to a specific immune response mechanism. Covalent …

The development of Haemophilus influenzae type b (Hib) conjugate vaccines has led to the
virtual elimination of systemic infections caused by that pathogen, has provided insights into …

Background. The development of a vaccine against Haemophilus influenzae type b (Hib)
was stimulated by its recognition as a major pathogen of early childhood. The first vaccine to …

OBJECTIVE: To review the epidemiology of Haemophilus influenzae type b (Hib) disease,
the first Hib vaccine and its limitations, the characteristics and clinical efficacy of the newer …

Publisher Summary This chapter discusses Haemophilus b conjugate vaccines.
Haemophilus influenzae type b (Hib), an encapsulated, Gram-negative, rod-like bacterium …

On September 22 to 25, 2002, a group of infectious disease specialists, public health
officials, and vaccine experts from 33 countries gathered in Scottsdale, Arizona, to discuss …

Haemophilus influenzae type b (Hib) was the major cause of invasive bacterial disease in
the United States and Canada before the introduction of Hib conjugate vaccines. Between …

The development ofHaemophilus influenzaetype b ((Hib) gate vaccines has led to the virtual
elimination of systemic infections caused by that pathogen, has provided insights into the …