The troponin complex and regulation of muscle contraction
CS Farah, FC Reinach - The FASEB Journal, 1995 - Wiley Online Library
In a wide variety of cellular settings, from organelle transport to muscle contraction, Ca2+
binding to members of the EF hand family of proteins controls the interaction between actin …
binding to members of the EF hand family of proteins controls the interaction between actin …
Structural basis for the regulation of muscle contraction by troponin and tropomyosin
A Galińska-Rakoczy, P Engel, C Xu, HS Jung… - Journal of molecular …, 2008 - Elsevier
The molecular switching mechanism governing skeletal and cardiac muscle contraction
couples the binding of Ca2+ on troponin to the movement of tropomyosin on actin filaments …
couples the binding of Ca2+ on troponin to the movement of tropomyosin on actin filaments …
A Direct Regulatory Role for Troponin T and a Dual Role for Troponin C in the Ca2+ Regulation of Muscle Contraction (∗)
JD Potter, Z Sheng, BS Pan, J Zhao - Journal of Biological Chemistry, 1995 - ASBMB
Troponin (Tn), containing three subunits: Ca 2+ binding (TnC), inhibitory (TnI), and
tropomyosin binding (TnT), plays a crucial role in the Ca 2+ regulation of vertebrate striated …
tropomyosin binding (TnT), plays a crucial role in the Ca 2+ regulation of vertebrate striated …
Regulatory properties of the NH2-and COOH-terminal domains of troponin T: ATPase activation and binding to troponin I and troponin C
The contraction of skeletal muscle is regulated by Ca 2+ binding to troponin C, which results
in an internal reorganization of the interactions within the troponin-tropomyosin complex …
in an internal reorganization of the interactions within the troponin-tropomyosin complex …
Structural basis for Ca2+-regulated muscle relaxation at interaction sites of troponin with actin and tropomyosin
Troponin and tropomyosin on actin filaments constitute a Ca2+-sensitive switch that
regulates the contraction of vertebrate striated muscle through a series of conformational …
regulates the contraction of vertebrate striated muscle through a series of conformational …
The role of troponins in muscle contraction
Troponin (Tn) is the sarcomeric Ca 2+ regulator for striated (skeletal and cardiac) muscle
contraction. On binding Ca 2+ Tn transmits information via structural changes throughout the …
contraction. On binding Ca 2+ Tn transmits information via structural changes throughout the …
Structural basis for the activation of muscle contraction by troponin and tropomyosin
W Lehman, A Galińska-Rakoczy, V Hatch… - Journal of Molecular …, 2009 - Elsevier
The molecular regulation of striated muscle contraction couples the binding and dissociation
of Ca2+ on troponin (Tn) to the movement of tropomyosin on actin filaments. In turn, this …
of Ca2+ on troponin (Tn) to the movement of tropomyosin on actin filaments. In turn, this …
Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent …
B Tripet, JE Van Eyk, RS Hodges - Journal of molecular biology, 1997 - Elsevier
To investigate the functional importance of the C-terminal residues 116 to 148 of troponin I
(TnI) in the Ca2+-dependent regulation of vertebrate skeletal muscle contraction, we have …
(TnI) in the Ca2+-dependent regulation of vertebrate skeletal muscle contraction, we have …
[引用][C] Structural aspects of troponin-tropomyosin regulation of skeletal muscle contraction
AS Zot, JD Potter - Annual review of biophysics and biophysical …, 1987 - annualreviews.org
REGULATION BY TROPONIN-TROPOMYOSIN 537 structural changes cause increased
interaction between actin and myosin, enhanced actomyosin ATPase activity, and …
interaction between actin and myosin, enhanced actomyosin ATPase activity, and …
Crystal structure of troponin C in complex with troponin I fragment at 2.3-Å resolution
DG Vassylyev, S Takeda, S Wakatsuki… - Proceedings of the …, 1998 - National Acad Sciences
Troponin (Tn), the complex of three subunits (TnC, TnI, and TnT), plays a key role in Ca2+-
dependent regulation of muscle contraction. To elucidate the interactions between the Tn …
dependent regulation of muscle contraction. To elucidate the interactions between the Tn …