Prognostic significance and molecular associations of tumor growth pattern in colorectal cancer

T Morikawa, A Kuchiba, ZR Qian… - Annals of surgical …, 2012 - Springer
Background Infiltrative growth pattern at the tumor margin has been associated with shorter
patient survival. However, little is known about the prognostic significance of tumor growth …

[HTML][HTML] Review of histopathological and molecular prognostic features in colorectal cancer

O Marzouk, J Schofield - Cancers, 2011 - mdpi.com
Prediction of prognosis in colorectal cancer is vital for the choice of therapeutic options.
Histopathological factors remain paramount in this respect. Factors such as tumor size …

[HTML][HTML] Does tumor size have its prognostic role in colorectal cancer? Re-evaluating its value in colorectal adenocarcinoma with different macroscopic growth pattern

W Dai, Y Li, X Meng, S Cai, Q Li, G Cai - International journal of surgery, 2017 - Elsevier
Background Few previous studies have taken the growth pattern into consideration when
analyzing the prognostic value of tumor size in colorectal cancer (CRC). Objective We …

[HTML][HTML] The tumor border configuration of colorectal cancer as a histomorphological prognostic indicator

VH Koelzer, A Lugli - Frontiers in oncology, 2014 - frontiersin.org
Histomorphological features of colorectal cancers (CRC) represent valuable prognostic
indicators for clinical decision making. The invasive margin is a central feature for …

[HTML][HTML] Predictive and prognostic effects of primary tumor size on colorectal cancer survival

OB Alese, W Zhou, R Jiang, K Zakka, Z Huang… - Frontiers in …, 2021 - frontiersin.org
Background Pathologic staging is crucial in colorectal cancer (CRC). Unlike the majority of
solid tumors, the current staging model does not use tumor size as a criterion. We evaluated …

Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases

T Ugai, N Akimoto, K Haruki, TA Harrison… - Journal of …, 2023 - Springer
Background The pathogenic effect of colorectal tumor molecular features may be influenced
by several factors, including those related to microbiota, inflammation, metabolism, and …

Tumor budding is an independent predictor of outcome in AJCC/UICC stage II colorectal cancer

J Betge, P Kornprat, MJ Pollheimer, RA Lindtner… - Annals of surgical …, 2012 - Springer
Background In colorectal cancer, the morphology of the invasive tumor margin may reflect
aggressiveness of tumor growth, thus providing important prognostic information. The tumor …

Tumor size as a prognostic factor in patients with stage IIa colon cancer

F Santullo, A Biondi, FCM Cananzi, V Fico… - The American Journal of …, 2018 - Elsevier
Background The aim of this study was to identify stage II colon cancer patients with a high
risk of recurrence. Methods All patients who underwent surgery for stage II colon cancer …

Prognostic significance and molecular features of signet-ring cell and mucinous components in colorectal carcinoma

K Inamura, M Yamauchi, R Nishihara, SA Kim… - Annals of surgical …, 2015 - Springer
Background Colorectal carcinoma (CRC) represents a group of histopathologically and
molecularly heterogeneous diseases, which may contain signet-ring cell component and/or …

[HTML][HTML] Genetic and epigenetic intra-tumour heterogeneity in colorectal cancer

HG Jones, G Jenkins, N Williams, P Griffiths… - World Journal of …, 2017 - Springer
Introduction Colorectal cancer (CRC) is a highly heterogeneous disease, with pathologically
similar cancers having completely different responses to treatment and patient survival. Intra …