[HTML][HTML] Effect of laryngopharyngeal anatomy on expiratory airflow and submicrometer particle deposition in human extrathoracic airways

X Si, J Xi, J Kim - Open Journal of Fluid Dynamics, 2013 - scirp.org
The objective of this study is to systematically assess the influences of the larynopharyneal
anatomical details on airflow and particle behaviors during exhalation by means of image …

Three-dimensional computational study of inspiratory aerosol flow through the larynx: the effect of glottal aperture modulation

IM Katz, TB Martonen, W Flaa - Journal of aerosol science, 1997 - Elsevier
In this paper surrogate geometry models for the larynx under sedentary, light, and heavy
breathing conditions are used as the basis of a finite element model to assess the effect of …

[HTML][HTML] Understanding the effects of inhaler resistance on particle deposition behaviour–A computational modelling study

X Cai, J Dong, L Milton-McGurk, A Lee, Z Shen… - Computers in Biology …, 2023 - Elsevier
Background and objective Understanding the impact of inhaler resistance on particle
transport and deposition in the human upper airway is essential for optimizing inhaler …

Investigating the effects of laryngotracheal stenosis on upper airway aerodynamics

T Cheng, D Carpenter, S Cohen, D Witsell… - The …, 2018 - Wiley Online Library
Objective Very little is known about the impact of laryngotracheal stenosis (LTS) on
inspiratory airflow and resistance, especially in air hunger states. This study investigates the …

Simulating the effect of individual upper airway anatomical features on drug deposition

Z Ma, A Kourmatzis, L Milton-McGurk, HK Chan… - International Journal of …, 2022 - Elsevier
This study aims to systematically isolate different anatomical features of the human pharynx
with the goal to investigate their independent influence on airflow dynamics and particle …

[HTML][HTML] Effects of vocal fold adduction on the particle deposition in the glottis: A numerical analysis and in vitro assessment

P Yu, C Xue, B Boeckenstedt, H Olsen… - Computers in Biology and …, 2023 - Elsevier
Background The efficacy of inhalation therapy depends on the drug deposition in the human
respiratory tract. This study investigates the effects of vocal fold adduction on the particle …

In silico assessment of mouth-throat effects on regional deposition in the upper tracheobronchial airways

PG Koullapis, L Nicolaou, SC Kassinos - Journal of Aerosol Science, 2018 - Elsevier
Regional deposition of inhaled medicines is a valuable metric of effectiveness in drug
delivery applications to the lung. In silico methods are now emerging as a valuable tool for …

Effects of the laryngeal jet on nano-and microparticle transport and deposition in an approximate model of the upper tracheobronchial airways

J Xi, PW Longest, TB Martonen - Journal of Applied …, 2008 - journals.physiology.org
The extent to which laryngeal-induced flow features penetrate into the upper
tracheobronchial (TB) airways and their related impact on particle transport and deposition …

Computational fluid dynamics model of laryngotracheal stenosis and correlation to pulmonary function measures

T Crosby, L Adkins, A McWhorter, M Kunduk… - Respiratory Physiology …, 2023 - Elsevier
Abstract 3D models of airway lumens were created from CT scans of 19 patients with
laryngotracheal stenosis. Computational fluid dynamics (CFD) simulations were completed …

Airflow and particle transport prediction through stenosis airways

P Singh, V Raghav, V Padhmashali, G Paul… - International journal of …, 2020 - mdpi.com
Airflow and particle transport in the human lung system is influenced by biological and other
factors such as breathing pattern, particle properties, and deposition mechanisms. Most of …