[PDF][PDF] Inhaled drug airflow patterns and particles deposition in the paediatric respiratory tract

Z Tyfa, P Jóźwik, D Obidowski… - Acta of …, 2020 - bibliotekanauki.pl
: The effectiveness of inhaled drugs is strictly related to areas reachable by drug particles.
Unless particles reach the desired part of the bronchial tree, their influence might not meet …

Inhaled particle deposition in unsteady-state respiratory flow at a numerically constructed model of the human larynx

H Takano, N Nishida, M Itoh, N Hyo… - Journal of aerosol …, 2006 - liebertpub.com
To evaluate the clinical effectiveness of aerosol therapy for the lower and upper respiratory
airways, particle deposition at the human laryngeal region has been analyzed with various …

Numerical simulation of human breathing and particle transport through a CT-based pulmonary airway geometry

RR Gruetzemacher III - 2014 - scholar.utc.edu
Chronic respiratory illness afflicts more than a billion people worldwide. In recent years
computational fluid dynamics (CFD) has been established as a paramount tool for studying …

A computational fluid dynamics model for drug delivery in a nasal cavity with inferior turbinate hypertrophy

XB Chen, HP Lee, VFH Chong… - Journal of aerosol …, 2010 - liebertpub.com
Background: Intranasal medications are commonly used in treating nasal diseases.
However, technical details of the correct usage of these medications for nasal cavity with …

Potential effects of inhaler mouthpiece size on particle deposition in the human upper airway

X Cai, B Ma, A Kourmatzis, F Salehi, A Lee… - Aerosol Science and …, 2022 - Taylor & Francis
Understanding the impact of inhaler mouthpiece sizes on particle transport and deposition in
the human upper airway is important to optimize inhaler designs toward improving the …

[HTML][HTML] Numerical study of the effects of bronchial structural abnormalities on respiratory flow distribution

S Yu, J Wang, X Sun, Y Liu - Biomedical engineering online, 2016 - Springer
Background The anatomical configurations of respiratory tract would be directly associated
with their ventilatory function. It is necessary to fully understand the association between …

Modeling flow in a compromised pediatric airway breathing air and heliox

M Mihaescu, E Gutmark, S Murugappan… - The …, 2008 - Wiley Online Library
Abstract Objectives/Hypothesis: The aim of this study was to perform computer simulations of
flow within an accurate model of a pediatric airway with subglottic stenosis. It is believed that …

Characterization of regional and local deposition of inhaled aerosol drugs in the respiratory system by computational fluid and particle dynamics methods

Á Farkas, I Balásházy, K Szőcs - Journal of aerosol medicine, 2006 - liebertpub.com
The present work describes the local deposition patterns of therapeutic aerosols in the
oropharyngeal airways, healthy and diseased bronchi and alveoli using computational fluid …

[HTML][HTML] Numerical and experimental analysis of inhalation airflow dynamics in a human pharyngeal airway

Y Fan, J Dong, L Tian, K Inthavong, J Tu - International Journal of …, 2020 - mdpi.com
This paper presents a computational and experimental study of steady inhalation in a
realistic human pharyngeal airway model. To investigate the intricate fluid dynamics inside …

Simulation of the effect of local obstructions and blockage on airflow and aerosol deposition in central human airways

A Farkas, I Balashazy - Journal of Aerosol Science, 2007 - Elsevier
Investigation of the effect of sidewall and carinal tumours, airway constrictions and airway
blockage on the inspiratory airflow and particle deposition in the large central human …