Glottis motion effects on the particle transport and deposition in a subject-specific mouth-to-trachea model: A CFPD study

J Zhao, Y Feng, CA Fromen - Computers in biology and medicine, 2020 - Elsevier
Abstract Background Computational Fluid-Particle Dynamics (CFPD) models have been
employed to predict lung aerosol dynamics for decades, estimating the delivery efficiency of …

Fluid flow and particle deposition analysis in a realistic extrathoracic airway model using unstructured grids

ST Jayaraju, M Brouns, S Verbanck, C Lacor - Journal of Aerosol Science, 2007 - Elsevier
An efficient Lagrangian particle tracking module is developed for unstructured grids to
analyze the deposition patterns in a CT based realistic extrathoracic airway model …

Aerosol transport throughout inspiration and expiration in the pulmonary airways

JM Oakes, SC Shadden, C Grandmont… - … journal for numerical …, 2017 - Wiley Online Library
Little is known about transport throughout the respiration cycle in the conducting airways. It
is challenging to appropriately describe the time‐dependent number of particles entering …

Numerical analysis on the flow characteristics considering the inspiratory flow rate in a human airway

KH Sung, HS Ryou - Journal of Biomedical Engineering Research, 2012 - koreascience.kr
The inspiratory flow rate of a human is changed with the amount of the workload. The flow
characteristic is affected by the inspiratory flow rate. In the flow field of airway, the both of …

Particle deposition in the human tracheobronchial airways due to transient inspiratory flow patterns

Z Li, C Kleinstreuer, Z Zhang - Journal of aerosol science, 2007 - Elsevier
Considering realistic tracheobronchial airways, transient airflow structures and micro-
particle deposition patterns were simulated with an in-house finite-volume code for typical …

Evaluation of a drift flux model for simulating submicrometer aerosol dynamics in human upper tracheobronchial airways

J Xi, PW Longest - Annals of biomedical engineering, 2008 - Springer
In this study, a hybrid drift flux velocity correction (DF-VC) model that accounts for both
submicrometer particle diffusion and inertia was extended to transient conditions and was …

[HTML][HTML] Numerical and experimental analysis of drug inhalation in realistic human upper airway model

M Momeni Larimi, A Babamiri, M Biglarian, A Ramiar… - Pharmaceuticals, 2023 - mdpi.com
The demand for a more efficient and targeted method for intranasal drug delivery has led to
sophisticated device design, delivery methods, and aerosol properties. Due to the complex …

A quasi-realistic computational model development and flow field study of the human upper and central airways

MR Rezazadeh, A Dastan, S Sadrizadeh… - Medical & Biological …, 2024 - Springer
The impact of drug delivery and particulate matter exposure on the human respiratory tract is
influenced by various anatomical and physiological factors, particularly the structure of the …

[HTML][HTML] Scale resolving simulations of the effect of glottis motion and the laryngeal jet on flow dynamics during respiration

J Emmerling, S Vahaji, DAV Morton, DF Fletcher… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective The movement of the respiratory walls has a significant
impact on airflow through the respiratory tract. The majority of computational fluid dynamics …

Transition and Laminar flows in a realistic geometry of human upper airway

R Tabe, R Rafee, MS Valipour… - Journal of Mechanics in …, 2022 - World Scientific
In this study, a realistic respiratory airway model extending from oral to the end of the
trachea including all the key details of the passage was produced. A series of CT scan …