Genomic diversity and hotspot mutations in 30,983 SARS-CoV-2 genomes: moving toward a universal vaccine for the “confined virus”?

T Alouane, M Laamarti, A Essabbar, M Hakmi… - Pathogens, 2020 - mdpi.com
The COVID-19 pandemic has been ongoing since its onset in late November 2019 in
Wuhan, China. Understanding and monitoring the genetic evolution of the virus, its …

Quality control of low-frequency variants in SARS-CoV-2 genomes

M Rayko, A Komissarov - BioRxiv, 2020 - biorxiv.org
During the current outbreak of COVID-19, research labs around the globe submit sequences
of the local SARS-CoV-2 genomes to the GISAID database to provide a comprehensive …

A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages

S Dellicour, K Durkin, SL Hong… - Molecular biology …, 2021 - academic.oup.com
Since the start of the COVID-19 pandemic, an unprecedented number of genomic
sequences of SARS-CoV-2 have been generated and shared with the scientific community …

CoVizu: Rapid analysis and visualization of the global diversity of SARS-CoV-2 genomes

RC Ferreira, E Wong, G Gugan, K Wade, M Liu… - Virus …, 2021 - academic.oup.com
Phylogenetics has played a pivotal role in the genomic epidemiology of severe acute
respiratory syndrome coronavirus 2, such as tracking the emergence and global spread of …

CoV-Spectrum: analysis of globally shared SARS-CoV-2 data to identify and characterize new variants

C Chen, S Nadeau, M Yared, P Voinov, N Xie… - …, 2022 - academic.oup.com
Abstract Summary The CoV-Spectrum website supports the identification of new SARS-CoV-
2 variants of concern and the tracking of known variants. Its flexible amino acid and …

Ongoing positive selection drives the evolution of SARS-CoV-2 genomes

Y Hou, S Zhao, Q Liu, X Zhang, T Sha… - Genomics …, 2022 - academic.oup.com
SARS-CoV-2 is a new RNA virus affecting humans and spreads extensively throughout the
world since its first outbreak in December, 2019. Whether the transmissibility and …

Temporal dynamics and evolution of SARS-CoV-2 demonstrate the necessity of ongoing viral genome sequencing in Ontario, Canada

CP Sjaarda, JL Guthrie, S Mubareka, JT Simpson… - Msphere, 2021 - Am Soc Microbiol
Genome-wide variation in SARS-CoV-2 reveals evolution and transmission dynamics which
are critical considerations for disease control and prevention decisions. Here, we review …

Temporal dynamics of SARS-CoV-2 mutation accumulation within and across infected hosts

AL Valesano, KE Rumfelt, DE Dimcheff, CN Blair… - PLoS …, 2021 - journals.plos.org
Analysis of SARS-CoV-2 genetic diversity within infected hosts can provide insight into the
generation and spread of new viral variants and may enable high resolution inference of …

Time series analysis of SARS-CoV-2 genomes and correlations among highly prevalent mutations

N Periwal, SB Rathod, S Sarma, GS Johar… - Microbiology …, 2022 - Am Soc Microbiol
The efforts of the scientific community to tame the recent pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) seem to have been diluted by the …

COVID-19 variants database: a repository for human SARS-CoV-2 polymorphism data

A Rakha, H Rasheed, Z Batool, J Akram, A Adnan, J Du - BioRxiv, 2020 - biorxiv.org
ABSTRACT COVID-19 is a newly communicable disease with a catastrophe outbreak that
affects all over the world. We retrieved about 8,781 nucleotide fragments and complete …