Serotonin in the gut: Blessing or a curse
S Banskota, JE Ghia, WI Khan - Biochimie, 2019 - Elsevier
Abstract Serotonin (5-hydroxytryptamine or 5-HT) once most extensively studied as a
neurotransmitter of the central nervous system, is seen to be predominantly secreted in the …
neurotransmitter of the central nervous system, is seen to be predominantly secreted in the …
Role of serotonin in gastrointestinal physiology and pathology.
C Cirillo, V Berghe, J Tack - Minerva endocrinologica, 2011 - europepmc.org
Serotonin is one of the most abundant molecules in the gastrointestinal tract and it plays a
crucial role in the regulation of several physiological functions, such as motility, secretion …
crucial role in the regulation of several physiological functions, such as motility, secretion …
Serotonin signalling in the gut—functions, dysfunctions and therapeutic targets
GM Mawe, JM Hoffman - Nature reviews Gastroenterology & hepatology, 2013 - nature.com
Abstract Serotonin (5-HT) has been recognized for decades as an important signalling
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …
molecule in the gut, but it is still revealing its secrets. Novel gastrointestinal functions of 5-HT …
Gut-derived serotonin and its emerging roles in immune function, inflammation, metabolism and the gut–brain axis
S Banskota, WI Khan - Current Opinion in Endocrinology …, 2022 - journals.lww.com
Emerging evidence regarding the role of peripheral 5-HT in the regulation of various
physiological and pathophysiological conditions opens up new targets for researchers to …
physiological and pathophysiological conditions opens up new targets for researchers to …
The multifaceted role of serotonin in intestinal homeostasis
The monoamine serotonin, 5-hydroxytryptamine (5-HT), is a remarkable molecule with
conserved production in prokaryotes and eukaryotes and a wide range of functions. In the …
conserved production in prokaryotes and eukaryotes and a wide range of functions. In the …
the many potential roles of intestinal serotonin (5‐hydroxytryptamine, 5‐HT) signalling in inflammatory bowel disease
Summary Background Serotonin (5‐hydroxytryptamine, 5‐HT) is an important mediator of
every major gut‐related function. Recent investigations also suggest that 5‐HT can influence …
every major gut‐related function. Recent investigations also suggest that 5‐HT can influence …
Non-conventional features of peripheral serotonin signalling—the gut and beyond
SN Spohn, GM Mawe - Nature reviews Gastroenterology & hepatology, 2017 - nature.com
Serotonin was first discovered in the gut, and its conventional actions as an intercellular
signalling molecule in the intrinsic and extrinsic enteric reflexes are well recognized, as are …
signalling molecule in the intrinsic and extrinsic enteric reflexes are well recognized, as are …
The role of serotonin and its receptors in activation of immune responses and inflammation
MS Shajib, WI Khan - Acta physiologica, 2015 - Wiley Online Library
Abstract Serotonin or 5‐hydroxytryptamine (5‐HT) is a neurotransmitter and hormone that
contributes to the regulation of various physiological functions by its actions in the central …
contributes to the regulation of various physiological functions by its actions in the central …
The mechanism of secretion and metabolism of gut-derived 5-hydroxytryptamine
N Liu, S Sun, P Wang, Y Sun, Q Hu… - International journal of …, 2021 - mdpi.com
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
reported to modulate the development and neurogenesis of the enteric nervous system, gut …
The diverse metabolic roles of peripheral serotonin
Abstract Serotonin (5-hydroxytryptamine or 5-HT) is a multifunctional bioamine with
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …
important signaling roles in a range of physiological pathways. Almost all of the 5-HT in our …