Making Molecules Make Themselves–the Chemistry of Artificial Replicators (Eur. J. Org. Chem. 5/2009)

A Vidonne, D Philp - European Journal of Organic Chemistry, 2009 - Wiley Online Library
The cover picture shows in the lower left corner the schematic representation of a
recognition‐mediated autocatalytic cycle that is capable of producing multiple copies of a …

Making molecules make themselves–the chemistry of artificial replicators

A Vidonne, D Philp - European Journal of Organic Chemistry, 2009 - Wiley Online Library
Examples of chemical systems capable of templating and catalyzing their own synthesis–so‐
called replicating systems–have begun to appear in the chemical literature over the last 20 …

Minimal self-replicating systems

A Robertson, AJ Sinclair, D Philp - Chemical Society Reviews, 2000 - pubs.rsc.org
Examples of chemical systems capable of templating and catalysing their own synthesis—
self-replicating systems—have begun to appear in the chemical literature over the last 15 …

Emergence of a new self-replicator from a dynamic combinatorial library requires a specific pre-existing replicator

Y Altay, M Tezcan, S Otto - Journal of the American Chemical …, 2017 - ACS Publications
Our knowledge regarding the early steps in the formation of evolvable life and what
constitutes the minimal molecular basis of life remains far from complete. The recent …

Existing Self‐Replicators Can Direct the Emergence of New Ones

Y Altay, M Altay, S Otto - Chemistry–A European Journal, 2018 - Wiley Online Library
The study of the interplay between different self‐replicating molecules constitutes an
important new phase in the synthesis of life and in unravelling the origin of life. Here we …

Probing Structural Effects on Replication Efficiency through Comparative Analyses of Families of Potential Self‐Replicators

E Kassianidis, RJ Pearson… - Chemistry–A European …, 2006 - Wiley Online Library
A formidable synthetic apparatus for the creation of nanoscale molecular structures and
supramolecular assemblies through molecular structures can potentially be created from …

Design and implementation of a highly selective minimal self-replicating system

E Kassianidis, D Philp - … Chemie-International Edition, 2006 - scholars.northwestern.edu
Self-direction: A rationally designed self-complementary template (see picture) is capable of
replication, thereby amplifying itself from a reaction mixture to the exclusion of its …

Self-replicating molecules: A second generation

EA Wintner, MM Conn, J Rebek Jr - Journal of the American …, 1994 - ACS Publications
The use of self-complementary structures in replication experiments is discussed, and a
second generation of self-replicating molecules is introduced. Key design elements of the …

Generalist versus Specialist Self‐Replicators

D Komáromy, DM Monzón, I Marić… - … A European Journal, 2024 - Wiley Online Library
Darwinian evolution, including the selection of the fittest species under given environmental
conditions, is a major milestone in the development of synthetic living systems. In this …

Parasitic Behavior of Self‐Replicating Molecules

M Altay, Y Altay, S Otto - Angewandte Chemie International …, 2018 - Wiley Online Library
Self‐replication plays a central role in the origin of life and in strategies to synthesize life de
novo. Studies on self‐replication have focused mostly on isolated systems, while the …