Cancer as a major public health problem is a big trouble to be cured at present in the world.
Thus, it is essential to discover better anticancer drugs to treat cancer patients. It has been …

Because cancers are caused by deregulation of hundreds of genes, an ideal anticancer
agent should target multiple gene products or signaling pathways simultaneously. Recently …

It is widely accepted that apoptosis is closely associated with cancer cell death. However,
whether autophagy induces tumor cell death has not been fully elucidated. Various studies …

Rottlerin has been reported to exert its anti-tumor activity in various types of human cancers.
However, the underlying molecular mechanism has not been fully elucidated. In the current …

Rottlerin, a polyphenolic compound, has been demonstrated to exhibit antitumor activity in
various types of human cancer. Several studies have revealed that rottlerin exerts its …

Rottlerin, a natural product isolated from Mallotus philippinensis, has been characterized as
an effective chemoprevention agent in inhibiting tumor cell growth. Although multiple studies …

Rottlerin, isolated from a medicinal plant Mallotus phillippinensis, has been demonstrated to
inhibit cellular growth and induce cytoxicity in glioblastoma cell lines through inhibition of …

The purpose of the study was to examine the molecular mechanisms by which rottlerin
inhibited growth of human pancreatic tumors in Balb C nude mice, and pancreatic cancer …

Studies have investigated the tumor suppressive role of rottlerin in carcinogenesis.
However, the molecular mechanisms of rottlerin-induced anti-tumor activity are largely …

Rottlerin, a polyphenolic compound derived from Mallotus philipinensis, has been reported
to exhibit anti-tumor activities in a variety of human malignancies including NSCLC (non …