Purpose Curcumin is an ideal chemopreventive and antitumor agent characterized by poor
bioavailability and low stability. The development of synthetic structural analogues like …

Curcumin and its analogs exhibited antileukemic activity either as single agent or in
combination therapy. Dimethoxycurcumin (DMC) is a more metabolically stable curcumin …

Curcumin is a known epigenetic modifier that demonstrated antitumor effect in different types
of cancer. The poor solubility and metabolic stability are major drawbacks that limit its …

Curcumin is a phytochemical with potent anti-neoplastic properties. The antitumoral effects
of curcumin in cells derived from chronic or acute myeloid leukemia have been already …

Purpose: The plant-derived compound curcumin has shown promising abilities as a cancer
chemoprevention and chemotherapy agent in vitro and in vivo but exhibits poor …

Curcumin has been documented to exert anticancer effects by interacting with altered
proliferative and apoptotic pathways in cancer models. In this study, we evaluated the …

Curcumin, a phenolic compound from the plant Curcuma longa L., has shown a wide-
spectrum of chemopreventive, antioxidant and antitumor properties. Although its promising …

Curcumin (Cur), is a pigment with antiproliferative activity but has some pharmacokinetic
limitations, which led researchers to look for more effective structure analogs. This work …

The unfavorable safety of existing anticancer medications and the issue of multidrug
resistance have fuelled the search for novel plant compounds as potential antineoplastic …

Dimethoxycurcumin (DiMC), a synthetic analog of curcumin, was shown to have
antiproliferative activity in human tumor cell lines. Therefore, we investigated its cytotoxic …