Water transport between CNS compartments: contributions of aquaporins and cotransporters

N MacAulay, T Zeuthen - Neuroscience, 2010 - Elsevier
Large water fluxes continuously take place between the different compartments of the brain
as well as between the brain parenchyma and the blood or cerebrospinal fluid. This water …

[HTML][HTML] The Role of Aquaporins in Epileptogenesis—A Systematic Review

L Bonosi, UE Benigno, S Musso, K Giardina… - International Journal of …, 2023 - mdpi.com
Aquaporins (AQPs) are a family of membrane proteins involved in the transport of water and
ions across cell membranes. AQPs have been shown to be implicated in various …

[HTML][HTML] Expression of aquaporins in Xenopus laevis oocytes and glial cells as detected by diffusion-weighted 1H NMR spectroscopy and photometric swelling assay

J Pfeuffer, S Bröer, A Bröer, M Lechte, U Flögel… - … et Biophysica Acta (BBA …, 1998 - Elsevier
Expression of aquaporins (AQP) and water permeability were studied in Xenopus laevis
oocytes and immobilized glial cells by a pulsed-field gradient spin echo NMR technique and …

Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain

S Nielsen, EA Nagelhus… - Journal of …, 1997 - Soc Neuroscience
Membrane water transport is critically involved in brain volume homeostasis and in the
pathogenesis of brain edema. The cDNA encoding aquaporin-4 (AQP4) water channel …

[HTML][HTML] Special Issue “Aquaporins in Brain Disease”

M Echevarría, P García-Miranda - International Journal of Molecular …, 2024 - mdpi.com
Water is an abundant and important component of the human brain, the homeostasis of
which is rigorously controlled. Aquaporins (AQPs) play a key role in mediating most water …

Aquaporin and brain diseases

J Badaut, AM Fukuda, A Jullienne, KG Petry - Biochimica et Biophysica …, 2014 - Elsevier
Background The presence of water channel proteins, aquaporins (AQPs), in the brain led to
intense research in understanding the underlying roles of each of them under normal …

Localization of aquaporin‐1 water channel in glial cells of the human peripheral nervous system

H Gao, C He, X Fang, X Hou, X Feng, H Yang, X Zhao… - Glia, 2006 - Wiley Online Library
The aquaporins (AQPs) are a family of water channel proteins with at least 13 mammalian
members (AQPs 0–12) expressed in diverse fluid transporting tissues. AQP1, AQP4, and …

Aquaporins in skeletal muscle: reassessment of the functional role of aquaporin‐4

A Frigeri, GP Nicchia, R Balena, B Nico… - The FASEB …, 2004 - Wiley Online Library
ABSTRACT Aquaporin‐4 (AQP4) is the major water channel of the neuromuscular system,
but its physiological function in both perivascular astrocytes and skeletal muscle …

Water channel proteins: from their discovery in Cluj-Napoca, Romania in 1985, to the 2003 Nobel Prize in chemistry and their implications in molecular medicine

G Benga - The Keio Journal of Medicine, 2006 - jstage.jst.go.jp
Water transport in cells and tissues is essential for life. When water molecules move into or
out of the cell or from one subcellular compartment to another they have to cross the cell …

Ontogeny of water transport in rat brain: Postnatal expression of the aquaporin‐4 water channel

H Wen, EA Nagelhus… - European Journal of …, 1999 - Wiley Online Library
Brain water transport is poorly understood at the molecular level, and marked changes occur
during brain development. As the aquaporin‐4 (AQP4) water channel protein is abundant in …