Oxyhaemoglobin increases the production of endothelin-1 by endothelial cells in culture

TM Cocks, E Malta, SJ King, RL Woods… - European journal of …, 1991 - Elsevier
Cultured endothelial cells from bovine thoracic aortas conditioned with serum-free culture
media released an endothelin-1 (ET)-1-like substance. Concentrations of ET-1-like material …

Effects of endothelin-1 on endothelial cells in the porcine coronary artery.

S Suzuki, J Kajikuri, A Suzuki, T Itoh - Circulation research, 1991 - Am Heart Assoc
The effects of endothelin-1 (ET-1) on endothelial cells from the porcine coronary artery were
investigated using cascade bioassay and radioimmunoassay methods. For comparison …

Production of endothelin by vascular smooth muscle cells

SM Kanse, K Takahashi, JB Warren… - Journal of …, 1991 - journals.lww.com
Endothelin (ET) production by cultured vascular smooth muscle cells isolated from rat and
rabbit aortae was measured by a specific radioimmunoassay. Vascular smooth muscle cells …

Production of endothelin by cultured porcine endothelial cells: modulation by adrenaline

M Kohno, K Murakawa, K Yokokawa… - Journal of …, 1989 - journals.lww.com
Cultured porcine endothelial cells derived from aortas spontaneously released
immunoreactive endothelin into the medium in a time-dependent manner. This release was …

Biosynthesis and modulation of endothelin from bovine pulmonary arterial endothelial cells

EH Ohlstein, A Arleth, M Ezekiel, S Horohonich… - Life sciences, 1990 - Elsevier
The biosynthesis and modulation of the vasoconstrictor peptide endothelin was studied in
the conditioned medium from cultured bovine pulmonary artery endothelial (BPAE) cells …

Interactions of endothelins and EDRF in bovine native endothelial cells: selective effects of endothelin-3

TD Warner, HH Schmidt… - American Journal of …, 1992 - journals.physiology.org
The tone of vascular smooth muscle is influenced by factors released from the endothelium,
including endothelin (ET)-1 and endothelium-derived relaxing factor (EDRF). To better …

Endothelin immunoreactivity in medium from cultured porcine aortic endothelial cells correlates with the biological activity

Y Matsumura, R Ikegawa, T Ohyama, K Hayashi… - Biochemical and …, 1989 - Elsevier
Using the radioimmunoassay (RIA) of endothelin (ET), we measured immunoreactive ET (IR-
ET) in culture medium of porcine aortic endothelial cells. The immunoreactivity in the …

Mechanism of oxyhemoglobin-induced release of endothelin-1 from cultured vascular endothelial cells and smooth-muscle cells

H Kasuya, BKA Weir, DM White, K Stefansson - Journal of neurosurgery, 1993 - thejns.org
✓ Release of endothelin-1 from cultured endothelial cells can be induced with
oxyhemoglobin (oxyHb). The present study was conducted to explore whether oxyHb affects …

Human cultured endothelial cells do secrete endothelin-1

M Clozel, W Fischli - Journal of Cardiovascular Pharmacology, 1989 - journals.lww.com
Summary Endothelin-1 (ET-1) has been identified in the conditioned medium of porcine
endothelial cells. Human endothelin (ET-1) cloned from a placenta cDNA library is similar to …

Stimulation of endogenous endothelin release in the anesthetized rat

DM Pollock, BJ Divish… - Journal of cardiovascular …, 1993 - journals.lww.com
Although many agents have been shown to stimulate release of endothelin (ET) in vitro, the
factors regulating and affecting production and release of ET in intact animals remain …