Non-genotoxic effects of selected pesticides and their disinfection by-products on gap junctional intercellular communication

BL Upham, B Boddy, X Xing, JE Trosko, SJ Masten - 1997 - Taylor & Francis
The presence of pesticides in drinking water poses a human health risk and disinfection can
either exacerbate or reduce these health risks by producing by-products that are either more …

Effects of cadmium on gap junctional intercellular communication in WB-F344 rat liver epithelial cells

SH Jeong, MH Cho, JH Cho - Human & experimental …, 2001 - journals.sagepub.com
Cadmium has been associated with a number of tumors but its role in tumor promotion has
not been elucidated clearly or the results obtained from various studies have been …

Gap junctions, homeostasis, and injury

A De Maio, VL Vega… - Journal of cellular …, 2002 - Wiley Online Library
Gap junctions (Gj) play an important role in the communication between cells of many
tissues. They are composed of channels that permit the passage of ions and low molecular …

Modifications in connexin expression in liver development and cancer

M Vinken, J De Kock, AG Oliveira… - Cell communication & …, 2012 - Taylor & Francis
The establishment of an elaborate gap junctional intercellular communication network,
especially between hepatocytes, is important for normal liver development. In fact, the …

Comparative in Vivo Hepatic Effects of Di-Isononyl Phthalate (DINP) and Related C7–C11 Dialkyl Phthalates on Gap Junctional Intercellular Communication (GJIC) …

JH Smith, JS Isenberg, G Pugh Jr… - Toxicological …, 2000 - academic.oup.com
The short-term hepatic effects of DINP (CAS 68515-48-0, designated DINP-1) in rats and
mice were evaluated at tumorigenic and nontumorigenic doses from previous chronic …

The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication

LAM Jansen, WMF Jongen - Carcinogenesis, 1996 - academic.oup.com
The effects of five non-mutagenic carcinogens—Aroclor 1260, benzoyl peroxide (BP),
phenobarbital (PB), 12-O-tetradecanoyl-phorbol-13-acetate (TPA) and 1, 1'-(2, 2, 2 …

Intercellular communication and human hepatocellular carcinoma

G Carruba, L Cocciadiferro, V Bellavia… - Annals of the New …, 2004 - Wiley Online Library
We have previously reported that gap junction‐mediated intercellular communication (GJIC)
can be restored in junctionally deficient human prostate epithelial cells, also suggesting that …

Colocalized alterations in connexin32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters

MJ Neveu, KL Babcock, EL Hertzberg, DL Paul… - Cancer research, 1994 - AACR
Direct intercellular signal transduction is achieved by the passage of small molecules
through gap junctions (GJ). Previous studies in our laboratory showed that the liver tumor …

[HTML][HTML] Gap junctional communication in tissue inflammation and repair

M Chanson, JP Derouette, I Roth, B Foglia… - … et Biophysica Acta (BBA …, 2005 - Elsevier
Local injury induces a complex orchestrated response to stimulate healing of injured tissues,
cellular regeneration and phagocytosis. Practically, inflammation is defined as a defense …

An improved long-term culture of rat hepatocytes to detect liver tumour-promoting agents: results with phenobarbital

M Mesnil, C Piccoli, H Yamasaki - European Journal of Pharmacology …, 1993 - Elsevier
Among various cocultures of hepatocytes with other cell types, we found that mouse
embryonal cells (BALB/c 3T3) are more effective in maintaining rat hepatocytes in vitro …