Glycol chitosan/fucoidan nanogels loaded with anti-inflammatory peptide KAFAK (GC/Fu@
KAFAK NGs) were fabricated based on the electrostatic interaction and genipin cross-linking …

Abstract Osteoarthritis (OA), as an “undead cancer”, causes a serious burden for both
individuals and society. In this study, a glycosaminoglycan-based injectable hydrogel was …

Synovial inflammation plays an important role in the early pathogenesis of osteoarthritis
(OA). Chitosan oligosaccharide (COS) has been shown to activate AMPK and suppress …

We developed a novel technique of bi-enzyme single-step hydrolysis, using recombinant
chitosanase (McChoA) and exo-β-D-glucosaminidase (AorCsxA) constructed previously in …

Aim: This study aimed to evaluate the antiarthritic and chondroprotective potentials of
Lakshadi Guggul (LG) and Cissus quadrangularis encapsulated in novel alginate-enclosed …

Synthetic hyaluronic acid (HA) containing a covalently integrated drug is capable of
releasing therapeutic molecules and is an attractive candidate for the intra-articular …

Glucosamine (GlcN) has been widely used to reduce joint pain and osteoarthritis
progression, but the efficacy of GlcN remains controversial because of the low GlcN …

This study aimed to evaluate the potential of an anti‐inflammatory polyethylene glycol (PEG)
hydrogel for osteoarthritis (OA) management in an OA in vitro model. Freshly isolated …

Activated macrophages are the primary targets in rheumatoid arthritis (RA) management.
So, we report efficacious, dual-functional Methotrexate (MTX) loaded folate-conjugated pH …

Platelet-rich plasma (PRP) is rich in growth factors and has commonly been utilized in the
repair and regeneration of damaged articular cartilage. However, the major drawbacks of …