Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of two diseases: adult T-
cell leukemia (ATL), a fatal T-lymphoproliferative disorder, and tropical spastic …

The human T-cell leukemia virus type I (HTLV-I)-encoded transcriptional activator protein
Tax is strongly implicated in HTLV-I pathogenesis. Tax regulates HTLV-I gene expression …

Adult T-cell leukemia (ATL) is an aggressive hematologic malignancy caused by human T-
cell leukemia virus type I (HTLV-1). Tax, encoded by the HTLV-1 pX region, has been …

Adult T-cell leukemia (ATL) is associated with prior infection with human T-cell leukemia
virus type 1 (HTLV-1). TAX, the major transactivator of HTLV-1, has been implicated in the …

Human T-cell leukemia virus type 1 (HTLV-1) Tax protein induces the expression of various
family members of the transcription factor AP-1, such as c-Jun, JunD, c-Fos, and Fra-1, at the …

Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 are retroviruses with similar
biological properties. Whereas HTLV-1 is the causative agent of an aggressive T-cell …

The human T-cell leukemia virus type I or HTLV-I is the causative agent of adult T-cell
leukemia. A protein encoded by HTLV-I, Tax, activates viral gene expression and is …

The Tax transactivator protein of human T-cell leukemia virus type 1 (HTLV-1) plays a
central role in the activation of viral gene expression. In addition, Tax is capable of activating …

The human T-cell leukemia virus type 1 (HTLV-1) transcriptional trans-activator Tax has
been demonstrated to have transforming activity in multiple cell culture and transgenic …

The human T-cell leukemia virus type 1 (HTLV-1) Tax protein activates the transcription of
several cellular genes. This function is thought to play a critical role in the Tax-dependent …