Local viscoelastic properties of live cells investigated using dynamic and quasi-static atomic force microscopy methods
A Cartagena, A Raman - Biophysical Journal, 2014 - cell.com
The measurement of viscoelasticity of cells in physiological environments with high spatio-
temporal resolution is a key goal in cell mechanobiology. Traditionally only the elastic …
temporal resolution is a key goal in cell mechanobiology. Traditionally only the elastic …
Fast, multi-frequency and quantitative nanomechanical mapping of live cells using the atomic force microscope
AX Cartagena-Rivera, WH Wang, RL Geahlen… - Scientific reports, 2015 - nature.com
A longstanding goal in cellular mechanobiology has been to link dynamic biomolecular
processes underpinning disease or morphogenesis to spatio-temporal changes in …
processes underpinning disease or morphogenesis to spatio-temporal changes in …
Mapping heterogeneity of cellular mechanics by multi-harmonic atomic force microscopy
The goal of mechanobiology is to understand the links between changes in the physical
properties of living cells and normal physiology and disease. This requires mechanical …
properties of living cells and normal physiology and disease. This requires mechanical …
Measuring biological materials mechanics with atomic force microscopy‐Determination of viscoelastic cell properties from stress relaxation experiments
Cells are complex, viscoelastic bodies. Their mechanical properties are defined by the
arrangement of semiflexible cytoskeletal fibers, their crosslinking, and the active remodeling …
arrangement of semiflexible cytoskeletal fibers, their crosslinking, and the active remodeling …
A one-step procedure to probe the viscoelastic properties of cells by Atomic Force Microscopy
YH Chim, LM Mason, N Rath, MF Olson, M Tassieri… - Scientific reports, 2018 - nature.com
The increasingly recognised importance of viscoelastic properties of cells in pathological
conditions requires rapid development of advanced cell microrheology technologies. Here …
conditions requires rapid development of advanced cell microrheology technologies. Here …
Measuring viscoelasticity of soft biological samples using atomic force microscopy
YM Efremov, T Okajima, A Raman - Soft matter, 2020 - pubs.rsc.org
Mechanical properties play important roles at different scales in biology. At the level of a
single cell, the mechanical properties mediate mechanosensing and mechanotransduction …
single cell, the mechanical properties mediate mechanosensing and mechanotransduction …
Noncontact viscoelastic imaging of living cells using a long-needle atomic force microscope with dual-frequency modulation
Imaging of surface topography and elasticity of living cells can provide insight into the roles
played by the cells' volumetric and mechanical properties and their response to external …
played by the cells' volumetric and mechanical properties and their response to external …
Mapping nanomechanical properties of live cells using multi-harmonic atomic force microscopy
The nanomechanical properties of living cells, such as their surface elastic response and
adhesion, have important roles in cellular processes such as morphogenesis, mechano …
adhesion, have important roles in cellular processes such as morphogenesis, mechano …
Single‐cell elastography: probing for disease with the atomic force microscope
KD Costa - Disease markers, 2004 - Wiley Online Library
The atomic force microscope (AFM) is emerging as a powerful tool in cell biology. Originally
developed for high‐resolution imaging purposes, the AFM also has unique capabilities as a …
developed for high‐resolution imaging purposes, the AFM also has unique capabilities as a …
Combined atomic force microscopy (AFM) and traction force microscopy (TFM) reveals a correlation between viscoelastic material properties and contractile prestress …
N Schierbaum, J Rheinlaender, TE Schäffer - Soft Matter, 2019 - pubs.rsc.org
Living cells exhibit a complex mechanical behavior, whose underlying mechanisms are still
largely unknown. Emerging from the molecular structure and dynamics of the cytoskeleton …
largely unknown. Emerging from the molecular structure and dynamics of the cytoskeleton …
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