MALAT1 lncRNA induces autophagy and protects brain microvascular endothelial cells against oxygen–glucose deprivation by binding to miR-200c-3p and …

S Wang, X Han, Z Mao, Y Xin, S Maharjan, B Zhang - Neuroscience, 2019 - Elsevier
There is growing evidence that long noncoding RNAs (lncRNAs) play important roles in
various biological processes. Metastasis-associated lung adenocarcinoma transcript 1 …

Long noncoding RNA Malat1 is a potent autophagy inducer protecting brain microvascular endothelial cells against oxygen-glucose deprivation/reoxygenation …

Z Li, J Li, N Tang - Neuroscience, 2017 - Elsevier
Brain microvascular endothelial cell (BMEC) injury induced by ischemia–reperfusion (I/R) is
the initial stage of blood–brain barrier (BBB) disruption, which results in a poor prognosis in …

[HTML][HTML] Down-regulation of Lncrna MALAT1 attenuates neuronal cell death through suppressing Beclin1-dependent autophagy by regulating Mir-30a in cerebral …

D Guo, J Ma, L Yan, T Li, Z Li, X Han… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: LncRNA metastasis associated lung adenocarcinoma transcript 1
(MALAT1) was reported to be highly expressed in an in vitro mimic of ischemic stroke …

[HTML][HTML] Long non-coding RNAMALAT1 knockdown alleviates cerebral ischemia/reperfusion injury of rats through regulating the miR-375/PDE4D axis

G Zhang, Q Wang, D Su, Y Xie - Frontiers in Neurology, 2021 - frontiersin.org
Objectives: Cerebral ischemic/reperfusion injury (CI/RI) is the clinical manifestation of
cerebral ischemic stroke, which severely affects the health and life of the patients. We aimed …

[HTML][HTML] LncRNA MALAT1 aggravates oxygen‐glucose deprivation/reoxygenation-induced neuronal endoplasmic reticulum stress and apoptosis via the miR-195a-5p …

Y Jia, L Yi, Q Li, T Liu, S Yang - Biological Research, 2021 - Springer
Background This study aimed to investigate the potential role and molecular mechanism of
lncRNA metastasis associated lung adenocarcinoma transcript 1 (MALAT1) in cerebral …

[HTML][HTML] The role of the lncRNA MALAT1 in neuroprotection against hypoxic/ischemic injury

L Wang, S Li, SS Stone, N Liu, K Gong, C Ren, K Sun… - Biomolecules, 2022 - mdpi.com
Hypoxic and ischemic brain injury can cause neurological disability and mortality, and has
become a serious public health problem worldwide. Long-chain non-coding RNAs are …

[HTML][HTML] Long noncoding RNA MALAT1 regulates apoptosis in ischemic stroke by sponging miR-205-3p and modulating PTEN expression

Q Gao, Y Wang - American journal of translational research, 2020 - ncbi.nlm.nih.gov
Ischemic stroke has been considered to be one of the major causes of disability worldwide
which related to multiple pathological processes including apoptosis. Metastasis associated …

LncRNA MALAT1 is neuroprotective in a rat model of spinal cord ischemia-reperfusion injury through miR-204 regulation

Y Qiao, C Peng, JI Li, D Wu… - Current Neurovascular …, 2018 - ingentaconnect.com
Background: This study was to investigate the neuroprotective effect of long noncoding
RNAs Metastasis associated lung adenocarcinoma transcript-1 (lncRNA MALAT-1) in Spinal …

[HTML][HTML] Long noncoding RNA MALAT1 inhibits apoptosis induced by oxygen-glucose deprivation and reoxygenation in human brain microvascular endothelial cells

JW Xin, YG Jiang - Experimental and therapeutic …, 2017 - spandidos-publications.com
Cerebral ischemia/reperfusion (I/R) injury leads to brain vascular dysfunction, which is
characterized by endothelial cell injury or death. Long noncoding (lnc) RNA metastasis …

Long noncoding RNA Malat1 regulates cerebrovascular pathologies in ischemic stroke

X Zhang, X Tang, K Liu, MH Hamblin… - Journal of …, 2017 - Soc Neuroscience
The study was designed to determine the role of long noncoding RNA (lncRNA), metastasis-
associated lung adenocarcinoma transcript 1 (Malat1), in ischemic stroke outcome. Primary …