Treating non-small-cell lung cancer first line with erlotinib monotherapy in elderly patients: discussion of a case series
M Reck - Oncology Research and Treatment, 2007 - karger.com
Non-small-cell lung cancer (NSCLC) predominantly occurs in the elderly, a group that has
been historically undertreated for various reasons such as perceived frailty and comorbidity …
been historically undertreated for various reasons such as perceived frailty and comorbidity …
Clinical effect of erlotinib as first-line treatment for Asian elderly patients with advanced non-small-cell lung cancer
XH Xu, J Su, XY Fu, F Xue, Q Huang, DJ Li… - Cancer chemotherapy …, 2011 - Springer
Purpose To evaluate the efficacy and toxicities of erlotinib as first-line treatment for Asian
elderly patients with advanced non-small-cell lung cancer (NSCLC). Patients and methods …
elderly patients with advanced non-small-cell lung cancer (NSCLC). Patients and methods …
Preliminary results from a phase II study of the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib in patients> 70 years of age with previously untreated …
BE Johnson, J Lucca, MS Rabin, TJ Lynch… - Journal of Clinical …, 2004 - ascopubs.org
7080 Background: Chemotherapy for patients≥ 70 years of age with advanced NSCLC can
be associated with greater toxicities than in younger patients. The identification of an …
be associated with greater toxicities than in younger patients. The identification of an …
Phase II trial of erlotinib in elderly patients (age> 70) with previously untreated advanced non-small cell lung cancer (NSCLC): An analysis of quality of life and …
DM Jackman, B Yeap, J Lucca, PA Ostler… - Journal of Clinical …, 2006 - ascopubs.org
7168 Background: Elderly patients derive survival benefit but significant toxicity from
chemotherapy for NSCLC. Erlotinib is associated with reasonable toxicity and has a survival …
chemotherapy for NSCLC. Erlotinib is associated with reasonable toxicity and has a survival …
Erlotinib treatment after platinum-based therapy in elderly patients with non-small-cell lung cancer in routine clinical practice–results from the ElderTac study
WM Brueckl, HJ Achenbach, JH Ficker, W Schuette - BMC cancer, 2018 - Springer
Background In this prospective non-interventional study, the effectiveness and tolerability of
erlotinib in elderly patients with non-small-cell lung cancer (NSCLC) after≥ 1 platinum …
erlotinib in elderly patients with non-small-cell lung cancer (NSCLC) after≥ 1 platinum …
Phase II study of the EGFR tyrosine kinase erlotinib in patients≥ 70 years of age with previously untreated advanced non-small cell lung carcinoma
D Jackman, J Lucca, P Fidias, MS Rabin… - Journal of Clinical …, 2005 - ascopubs.org
7148 Background: Chemotherapy for patients≥ 70 with advanced NSCLC is associated
with survival benefits but with increased toxicity compared with younger patients. Erlotinib …
with survival benefits but with increased toxicity compared with younger patients. Erlotinib …
Open, randomized, multi-center phase II study comparing efficacy and tolerability of Erlotinib vs. Carboplatin/Vinorelbin in elderly patients (> 70 years of age) with …
DF Heigener, KM Deppermann, JV Pawel, JR Fischer… - Lung Cancer, 2014 - Elsevier
Background Targeting the epidermal-growth-factor-receptor (EGFR) in non-small cell lung
cancer (NSCLC) is an established treatment option with less toxicity compared to …
cancer (NSCLC) is an established treatment option with less toxicity compared to …
Erlotinib and gefitinib for elderly patients with advanced non-small-cell lung cancer
A Passaro, D Alesini, A Pochesci… - Anti-Cancer Agents in …, 2014 - ingentaconnect.com
Erlotinib and gefitinib are tyrosine kinase inhibitors (TKI) associated with the EGFR, which is
involved in cell proliferation, growth, migration, invasion and survival, and has been found to …
involved in cell proliferation, growth, migration, invasion and survival, and has been found to …
A phase II trial of erlotinib monotherapy for pretreated elderly patients with advanced EGFR wild-type non-small cell lung cancer
H Minemura, H Yokouchi, K Azuma, K Hirai… - BMC Research …, 2015 - Springer
Background Erlotinib is an epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitor, which is an effective treatment for patients with non-small cell lung cancer …
inhibitor, which is an effective treatment for patients with non-small cell lung cancer …
Efficacy of erlotinib and its effects on the quality of life of older patients with epidermal growth factor receptor‐mutant non‐small cell lung cancer: A prospective …
Y Tsubata, T Masuda, K Hamai… - Geriatrics & …, 2021 - Wiley Online Library
Aim Gefitinib and erlotinib are efficacious and safe for older patients with epidermal growth
factor receptor‐mutant non‐small cell lung cancer. However, prolonged use of epidermal …
factor receptor‐mutant non‐small cell lung cancer. However, prolonged use of epidermal …