Computational studies and synthesis of 131 iodine-labeled nocardiotide A analogs as a peptide-based theragnostic radiopharmaceutical ligand for cancer targeting …

RJ Sugiharti, R Maharani, F Kurniawan… - RSC …, 2024 - pubs.rsc.org
Radiolabeled peptides belong to a highly specific group of radiotracers used in oncology,
particularly for diagnostics and cancer therapy. With the notable advantages of high binding …

Synthesis and anticancer evaluation of [d-Ala]-nocardiotide A

R Maharani, MI Muhajir, JM Dirgantara, A Hardianto… - RSC …, 2024 - pubs.rsc.org
Cancer is currently one of the biggest causes of death in the world. Like some
microorganisms, cancer cells also develop resistance to various chemotherapy drugs and …

Synthesis, in silico and biodistribution studies of a novel 47Sc-radiolabeled α-amino acid ester derivative attached to pyrazine and tetrazole rings for tumor targeted …

MA Gizawy, HA Shamsel-Din, MMT El-Tahawy… - Radiochimica …, 2024 - degruyter.com
Recently, tumor-targeted radionuclide therapy has gained much recognition for the
treatment of metastasized cancer. There is a growing interest in using the theranostic …

In silico and In vitro investigation of a likely pathway for anti-cancerous effect of Thrombocidin-1 as a novel anticancer peptide

A Tanhaian, E Mohammadi… - Protein and peptide …, 2020 - ingentaconnect.com
Background: Antimicrobial and antifungal activities of Thrombocidin-1 (TC-1) is shown
previously, however, the anti-cancerous feature of this peptide is still uncovered. Objective …

In Silico study of anticancer and antimicrobial peptides derived from Cycloviolacin O2 (CyO2)

N Abbas, HD Tan, BH Goh, WH Yap… - … Research in Applied …, 2023 - research.monash.edu
Cancer is considered a global threat to public health as one of the leading causes of
premature deaths in most countries worldwide. Chemotherapy in cancer has reached a …

99mTc‐HYNIC‐(Ser)3‐J18 peptide: A radiotracer for non‐small‐cell lung cancer targeting

Z Shaghaghi, SM Abedi… - Chemical Biology & …, 2018 - Wiley Online Library
Radiolabeled peptide could be a useful tool for the diagnosis of non‐small‐cell lung cancer
(NSCLC). In this study, HYNIC‐(Ser) 3‐J18 peptide was labeled with 99mTc using …

In silico approach: biological prediction of nordentatin derivatives as anticancer agent inhibitors in the cAMP pathway

MI Abdjan, NS Aminah, I Siswanto, TM Thant… - RSC …, 2020 - pubs.rsc.org
A combination of computational techniques has been carried out to predict the binding of
nordentatin derivatives based on pyranocoumarin semi-synthesis with the target protein …

[HTML][HTML] Tricine co-ligand improved the efficacy of 99mTc-HYNIC-(Ser) 3-J18 peptide for targeting and imaging of non-small-cell lung cancer

Z Shaghaghi, SM Abedi, SJ Hosseinimehr - Biomedicine & …, 2018 - Elsevier
The early diagnosis of non-small cell lung cancer (NSCLC) is important for increasing
survival rate and improving quality life of patients. The aim of this study was to investigate …

De novo design of AC-P19M, a novel anticancer peptide with apoptotic effects on lung cancer cells and anti-angiogenic activity

MK Shin, BY Jang, KB Bu, SH Lee, DH Han… - International Journal of …, 2022 - mdpi.com
Despite the current developments in cancer therapeutics, efforts to excavate new anticancer
agents continue rigorously due to obstacles, such as side effects and drug resistance …

[PDF][PDF] Predicting, designing, characterization and evaluation of a new novel anticancer peptide SSVAM-9 against the lung carcinoma, an insilico approach

S Kalajirao, SA Ramakrishnan… - J. Med. Pharm. Allied Sci, 2023 - jmpas.com
Several anticancer drugs are getting resisted by the cancer cell and treatment like
chemotherapy, radiation causes serious side effects. In immunomodulatory treatment the …