FleQ DNA binding consensus sequence revealed by studies of FleQ-dependent regulation of biofilm gene expression in Pseudomonas aeruginosa
C Baraquet, CS Harwood - Journal of bacteriology, 2016 - Am Soc Microbiol
The transcription factor FleQ from Pseudomonas aeruginosa derepresses expression of
genes involved in biofilm formation when intracellular levels of the second messenger cyclic …
genes involved in biofilm formation when intracellular levels of the second messenger cyclic …
The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response …
C Baraquet, K Murakami, MR Parsek… - Nucleic acids …, 2012 - academic.oup.com
Abstract Bis-(3′–5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) modulates the
transition between planktonic and biofilm life styles. In response to c-di-GMP, the enhancer …
transition between planktonic and biofilm life styles. In response to c-di-GMP, the enhancer …
[HTML][HTML] FleQ of Pseudomonas putida KT2440 is a multimeric cyclic diguanylate binding protein that differentially regulates expression of biofilm matrix components
MA Molina-Henares, MI Ramos-González… - Research in …, 2017 - Elsevier
The intracellular signal molecule cyclic di-GMP (c-di-GMP) is an important element in
regulation of biofilm formation by bacteria. In Pseudomonas aeruginosa, FleQ functions as a …
regulation of biofilm formation by bacteria. In Pseudomonas aeruginosa, FleQ functions as a …
Mechanistic insights into c-di-GMP–dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa
BY Matsuyama, PV Krasteva… - Proceedings of the …, 2016 - National Acad Sciences
Bacterial biofilm formation during chronic infections confers increased fitness, antibiotic
tolerance, and cytotoxicity. In many pathogens, the transition from a planktonic lifestyle to …
tolerance, and cytotoxicity. In many pathogens, the transition from a planktonic lifestyle to …
Cyclic diguanosine monophosphate represses bacterial flagella synthesis by interacting with the Walker A motif of the enhancer-binding protein FleQ
C Baraquet, CS Harwood - Proceedings of the National …, 2013 - National Acad Sciences
The transcription factor FleQ is a bacterial AAA+ ATPase enhancer-binding protein that is
the master activator of flagella gene expression in the opportunistic bacterial pathogen …
the master activator of flagella gene expression in the opportunistic bacterial pathogen …
Complex interplay between FleQ, cyclic diguanylate and multiple σ factors coordinately regulates flagellar motility and biofilm development in Pseudomonas putida
A Jiménez-Fernández, A López-Sánchez… - PLoS …, 2016 - journals.plos.org
Most bacteria alternate between a free living planktonic lifestyle and the formation of
structured surface-associated communities named biofilms. The transition between these …
structured surface-associated communities named biofilms. The transition between these …
Genetic Analysis of the AdnA Regulon in Pseudomonas fluorescens: Nonessential Role of Flagella in Adhesion to Sand and Biofilm Formation
EA Robleto, I López-Hernández, MW Silby… - Journal of …, 2003 - Am Soc Microbiol
AdnA is a transcription factor in Pseudomonas fluorescens that affects flagellar synthesis,
biofilm formation, and sand adhesion. To identify the AdnA regulon, we used a promoterless …
biofilm formation, and sand adhesion. To identify the AdnA regulon, we used a promoterless …
Fis overexpression enhances Pseudomonas putida biofilm formation by regulating the ratio of LapA and LapF
H Moor, A Teppo, A Lahesaare, M Kivisaar… - …, 2014 - microbiologyresearch.org
Bacteria form biofilm as a response to a number of environmental signals that are mediated
by global transcription regulators and alarmones. Here we report the involvement of the …
by global transcription regulators and alarmones. Here we report the involvement of the …
A transcriptional activator, FleQ, regulates mucin adhesion and flagellar gene expression in Pseudomonas aeruginosa in a cascade manner
SK Arora, BW Ritchings, EC Almira, S Lory… - Journal of …, 1997 - Am Soc Microbiol
Previous work has demonstrated that fleR, the gene for a transcriptional activator belonging
to the NtrC subfamily of response regulators, is involved in the regulation of mucin adhesion …
to the NtrC subfamily of response regulators, is involved in the regulation of mucin adhesion …
The REC domain mediated dimerization is critical for FleQ from Pseudomonas aeruginosa to function as a c-di-GMP receptor and flagella gene regulator
T Su, S Liu, K Wang, K Chi, D Zhu, T Wei… - Journal of structural …, 2015 - Elsevier
FleQ is an AAA+ ATPase enhancer-binding protein that regulates both flagella and biofilm
formation in the opportunistic pathogen Pseudomonas aeruginosa. FleQ belongs to the NtrC …
formation in the opportunistic pathogen Pseudomonas aeruginosa. FleQ belongs to the NtrC …
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