The objective of this study was to evaluate differential expression of innate and adaptive
immune genes, including immunoglobulin, immune cell receptor, cytokine, inflammatory …

Aquatic animals immune response to pathogenic is a hotspot and related to high-quality
development of aquaculture industry and the conservation of fisheries resources …

As an important endogenous cytokine in mammals, interferon-γ (IFNγ) primes and
significantly enhances the recognition and response of TLRs to pathogen-associated …

In the present study, the interleukin-6 gene (IL-6) cDNA in blunt snout bream (Megalobrama
amblycephala) was identified and its expression profiles under ammonia stress and …

Rel/NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) genes are
evolutionarily conserved and play a pivotal role in several physiological events. They have …

Mucosal organs are principle portals of entry for microbial invasion and as such developing
protective vaccines against these pathogens can serve as a first line of defense against …

Turbot Scophthalmus maximus is an important mariculture fish species with high economic
value. However, the bacterial diseases caused by Vibrio anguillarum infection bring huge …

We performed RNA sequencing, identified components of the immune system and mapped
early immune responses of lumpfish (Cyclopterus lumpus) leukocytes following in vitro …

Amphioxus, a cephalochordate, is a key model animal for studying the evolution of
vertebrate immunity. Recently, studies have revealed that microRNA (miRNA) expression …

Abstract Interleukin-6 (IL-6) is a pleiotropic inflammatory cytokine, which plays a dual role in
mammalian inflammation through both classical signaling (IL-6 binds to IL-6 receptor/IL-6R) …