Gut emotions-mechanisms of action of probiotics as novel therapeutic targets for depression and anxiety disorders

A Slyepchenko, A F. Carvalho, D S. Cha… - CNS & Neurological …, 2014 - benthamdirect.com
A priority clinical and research agenda in mood and anxiety disorders is to identify
determinants that influence illness trajectory and outcome. Over the past decade, studies …

Gut microbiota in anxiety and depression: unveiling the relationships and management options

A Kumar, J Pramanik, N Goyal, D Chauhan… - Pharmaceuticals, 2023 - mdpi.com
The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in developing …

[HTML][HTML] Psychobiotics as a novel strategy for alleviating anxiety and depression

R Zou, P Tian, M Xu, H Zhu, J Zhao, H Zhang… - Journal of Functional …, 2021 - Elsevier
Anxiety and depression have become major health challenges in recent decades.
Accumulating evidence suggests that gut microbial dysbiosis may have a profound effect on …

A reciprocal link between gut microbiota, inflammation and depression: a place for probiotics?

A Eltokhi, IE Sommer - Frontiers in Neuroscience, 2022 - frontiersin.org
Depression is a severe mental disorder that places a significant economic burden on public
health. The reciprocal link between the trillions of bacteria in the gut, the microbiota, and …

Probiotics' Effects in the Treatment of Anxiety and Depression: A Comprehensive Review of 2014–2023 Clinical Trials

E Merkouris, T Mavroudi, D Miliotas, D Tsiptsios… - Microorganisms, 2024 - mdpi.com
Changes in the gut microbiome can affect cognitive and psychological functions via the
microbiota–gut–brain (MGB) axis. Probiotic supplements are thought to have largely positive …

[HTML][HTML] The gut-brain axis: the missing link in depression

A Evrensel, ME Ceylan - Clinical Psychopharmacology and …, 2015 - ncbi.nlm.nih.gov
The gut microbiota is essential to human health and the immune system and plays a major
role in the bidirectional communication between the gut and the brain. Based on evidence …

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

M Pirbaglou, J Katz, RJ de Souza, JC Stearns… - Nutrition research, 2016 - Elsevier
Gastrointestinal microbiota, consisting of microbial communities in the gastrointestinal tract,
play an important role in digestive, metabolic, and immune functioning. Preclinical studies …

Gut–brain axis and mood disorder

L Liu, G Zhu - Frontiers in psychiatry, 2018 - frontiersin.org
Humans have over 100 trillion bacteria, highly abundant in the intestinal tract. Evidence
suggests that intestinal microbiota is associated with the neuro-endocrine-immune pathways …

Exploring the role and potential of probiotics in the field of mental health: major depressive disorder

D Johnson, S Thurairajasingam, V Letchumanan… - Nutrients, 2021 - mdpi.com
The field of probiotic has been exponentially expanding over the recent decades with a
more therapeutic-centered research. Probiotics mediated microbiota modulation within the …

Gut microbiota in mental health and depression: Role of pre/pro/synbiotics in their modulation

HN Methiwala, B Vaidya, VK Addanki, M Bishnoi… - Food & Function, 2021 - pubs.rsc.org
The microbiome residing in the human gut performs a wide range of biological functions.
Recently, it has been elucidated that a change in dietary habits is associated with alteration …