BACKGROUND. Whole-body hypothermia reduced the frequency of death or
moderate/severe disabilities in neonates with hypoxic-ischemic encephalopathy in a …

Background Whether hypothermic therapy improves neurodevelopmental outcomes in
newborn infants with asphyxial encephalopathy is uncertain. Methods We performed a …

Therapeutic hypothermia holds promise as a rescue neuroprotective strategy for hypoxic-
ischemic injury, but the incidence of severe neurologic sequelae with hypothermia is …

Background In the Total Body Hypothermia for Neonatal Encephalopathy Trial (TOBY),
newborns with asphyxial encephalopathy who received hypothermic therapy had improved …

In this article, we review the childhood outcomes of neonates with birth depression and/or
hypoxic-ischemic encephalopathy. The outcomes of these children prior to the era of …

Objective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal
mortality and neurodisability. We aimed to determine the incidence of HIE and management …

Importance Hypothermia for 72 hours at 33.5° C for neonatal hypoxic-ischemic
encephalopathy reduces death or disability, but rates continue to be high. Objective To …

Although selective or whole body cooling combined with optimal intensive care improves
outcomes following neonatal encephalopathy in high-income countries, the safety and …

Objective To evaluate the safety and short-term outcomes of preterm neonates born at 34-35
weeks gestation with hypoxic-ischemic encephalopathy (HIE) treated with therapeutic …

Moderate to severe hypoxic–ischemic injury in newborn infants, manifested as
encephalopathy immediately or within hours after birth, is associated with a high risk of …