Introduction: Prediction of neurodevelopmental outcome in infants with hypoxic-ischemic
encephalopathy remains an important challenge. Various studies have shown that the …

Therapeutic hypothermia is now considered the standard of care for neonates with neonatal
encephalopathy due to perinatal asphyxia. Outcomes following hypothermia treatment are …

OBJECTIVE. The goal of this study was to evaluate the role of factors that may determine the
efficacy of treatment with delayed head cooling and mild systemic hypothermia for neonatal …

Abstract Purpose of Review Therapeutic hypothermia reduces death or disability in term and
near-term infants with moderate-severe hypoxic-ischemic encephalopathy. Nevertheless …

Perinatal hypoxic-ischemic encephalopathy is a leading cause of neonatal death and
disability. Therapeutic hypothermia significantly reduces death and major disability …

Background Delay in implementing new treatments into clinical practice results in
considerable health and economic opportunity costs. Data from the UK TOBY Cooling …

Therapeutic hypothermia is a standard of care for infants≥ 36 weeks gestational age (GA)
with moderate-to-severe hypoxic-ischemic encephalopathy. Because some studies included …

Hypoxia–ischemia before or around the time of birth occurs in approximately 2/1000 live
births and is associated with a high risk of death or lifelong disability. Therapeutic …

OBJECTIVE: Mild hypothermia after perinatal hypoxic-ischemic encephalopathy (HIE)
reduces neurologic sequelae without significant adverse effects, but studies are needed to …