Candidate gene–environment interaction research: Reflections and recommendations
Studying how genetic predispositions come together with environmental factors to contribute
to complex behavioral outcomes has great potential for advancing the understanding of the …
to complex behavioral outcomes has great potential for advancing the understanding of the …
Gene-environment interaction in psychological traits and disorders
DM Dick - Annual review of clinical psychology, 2011 - annualreviews.org
There has been an explosion of interest in studying gene-environment interactions (GxE) as
they relate to the development of psychopathology. In this article, I review different …
they relate to the development of psychopathology. In this article, I review different …
Gene× environment interactions: from molecular mechanisms to behavior
T Halldorsdottir, EB Binder - Annual Review of Psychology, 2017 - annualreviews.org
Gene-by-environment interactions (G× Es) can provide important biological insights into
psychiatric disorders and may consequently have direct clinical implications. In this review …
psychiatric disorders and may consequently have direct clinical implications. In this review …
Gene-environment interaction
SB Manuck, JM McCaffery - Annual review of psychology, 2014 - annualreviews.org
With the advent of increasingly accessible technologies for typing genetic variation, studies
of gene-environment (G× E) interactions have proliferated in psychological research. Among …
of gene-environment (G× E) interactions have proliferated in psychological research. Among …
A critical review of the first 10 years of candidate gene-by-environment interaction research in psychiatry
Objective: Gene-by-environment interaction (G× E) studies in psychiatry have typically been
conducted using a candidate G× E (cG× E) approach, analogous to the candidate gene …
conducted using a candidate G× E (cG× E) approach, analogous to the candidate gene …
Gene× environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution
MC Keller - Biological psychiatry, 2014 - Elsevier
Candidate gene× environment (G× E) interaction research tests the hypothesis that the
effects of some environmental variable (eg, childhood maltreatment) on some outcome …
effects of some environmental variable (eg, childhood maltreatment) on some outcome …
Gene–environment interactions in genome‐wide association studies: current approaches and new directions
SJ Winham, JM Biernacka - Journal of Child Psychology and …, 2013 - Wiley Online Library
Background Complex psychiatric traits have long been thought to be the result of a
combination of genetic and environmental factors, and gene–environment interactions are …
combination of genetic and environmental factors, and gene–environment interactions are …
Mind the gap: Why many geneticists and psychological scientists have discrepant views about gene–environment interaction (G× E) research.
As our field seeks to elucidate the biopsychosocial etiologies of mental health disorders,
many traditional psychological and social science researchers have added, or plan to add …
many traditional psychological and social science researchers have added, or plan to add …
Gene–environment interplay and psychopathology: Multiple varieties but real effects
M Rutter, TE Moffitt, A Caspi - Journal of child Psychology and …, 2006 - Wiley Online Library
Gene–environment interplay is a general term that covers several divergent concepts with
different meanings and different implications. In this review, we evaluate research evidence …
different meanings and different implications. In this review, we evaluate research evidence …
Strategy for investigating interactions between measured genes and measured environments
TE Moffitt, A Caspi, M Rutter - Archives of general psychiatry, 2005 - jamanetwork.com
The purpose of this article is to promote research that tests hypotheses of measured gene-
environment interaction (GxE). A GxE occurs when the effect of exposure to an …
environment interaction (GxE). A GxE occurs when the effect of exposure to an …