The cure rate for metastatic or relapsed osteosarcoma has not substantially improved over
the past decades despite the exploitation of multimodal treatment approaches, allowing long …

Osteosarcoma is one of the most common primary malignant tumors of bone. The
combination of chemotherapy and surgery makes the prognosis better than before, but …

Osteosarcoma (OS) is the most common primary malignancy of the bone and has a high
propensity for local invasion and metastasis. Although combining surgery with …

Osteosarcoma, a malignant bone tumor predominantly affecting children and adolescents,
presents significant therapeutic challenges, particularly in metastatic or recurrent cases …

Even though combining surgery with chemotherapy has significantly improved the prognosis
of osteosarcoma patients, advanced, metastatic, or recurrent osteosarcomas are often non …

T-cell immunotherapy may offer an approach to improve outcomes for patients with
osteosarcoma who fail current therapies. In addition, it has the potential to reduce treatment …

Osteosarcoma is the most common primary malignancy of bone. Although outcomes of
patients with osteosarcoma have improved since the introduction of chemotherapy …

Osteosarcoma (OS) is a primary malignant bone tumor that emanates from mesenchymal
cells, commonly found in the epiphyseal end of long bones. The highly recurrent and …

Immunosuppressive elements within the tumor microenvironment are the primary drivers of
tumorigenesis and malignant advancement. The presence, as well as the crosstalk between …

Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …