[HTML][HTML] Identification of natural inhibitor against L1 β-lactamase present in Stenotrophomonas maltophilia

D Jade, MA Harrison, S Sugumar - Journal of Molecular Modeling, 2022 - Springer
Antibiotic resistance is threatening the medical industry in treating microbial infections. Many
organisms are acquiring antibiotic resistance because of the continuous use of the same …

In-silico virtual screening for identification of potent inhibitor for L2-β-lactamase from Stenotrophomonas maltophilia through molecular docking, molecular dynamics …

R Sharma, D Jade, S Mohan, R Chandel… - Journal of …, 2021 - Taylor & Francis
Abstract Stenotrophomonas maltophilia, a Multiple-Drug-Resistant proteobacterium found in
healthy normal flora and fauna with an aerobic and non-fermentative respiratory process, is …

Insight into the screening of potential beta-lactamase inhibitors as anti-bacterial chemical agents through pharmacoinformatics study

P Parida, S Bhowmick, A Saha… - Journal of Biomolecular …, 2021 - Taylor & Francis
Drug resistance is an unsolved and major concern in the bacterial infection. Continuous
development of drug-resistance to the antibiotics exponentially rises the danger of bacterial …

In silico modeling for Identification of promising antimicrobials of Herbal origin against highly virulent pathogenic strains of bacteria like New Delhi Metallo-beta …

P Thakur, R Chawla, R Goel, R Arora - International Journal of …, 2013 - arastirmax.com
Drug resistance has mushroomed up after advent of every major class of antimicrobial
drugs, varying in time from as short as 1 year (penicillin) to> 10 years. Organisms associated …

Identification of Phytochemicals with Inhibitory Potential Against Beta-lactamase Enzymes via Computer-aided Approach

GC Nwokebu, AB Adesina, CN Isibor, SA Aigbepue… - Bioorganic …, 2024 - Elsevier
Introduction Antibacterial drugs have been widely used for the past century to treat diseases,
but their efficacy has been limited by multi-resistant pathogens, particularly those that utilize …

Designing of inhibitors against CTX-M-15 type β-lactamase: potential drug candidate against β-lactamases-producing multi-drug-resistant bacteria

A Ali, Danishuddin, L Maryam… - Journal of …, 2018 - Taylor & Francis
CTX-M-15 are the most prevalent types of β-lactamases that hydrolyze almost all antibiotics
of β-lactam group lead to multiple-antibiotic resistance in bacteria. Three β-lactam inhibitors …

Discovery of phyto-compounds as novel inhibitors against NDM-1 and VIM-1 protein through virtual screening and molecular modelling

B Kar, CN Kundu, S Pati… - Journal of Biomolecular …, 2023 - Taylor & Francis
Amid the rise of multi-drug resistance among bacterial pathogens, the drying of the
development pipeline of new antibiotics is worrisome. In search of new effective alternatives …

[HTML][HTML] In silico study of essential oil of Bambusa vulgaris leaves as an anti beta-lactamase compound

PW Anggini, SA Amanina, SR Asyura… - Molecular and Cellular …, 2022 - cellbiopharm.com
Background: Klebsiella pneumoniae is known as an extended spectrum beta (β)-lactamases
(ESBLs)-producing bacteria, which produces enzymes that cause resistance to β-lactam …

Identification of potential inhibitor against CTX-M-3 and CTX-M-15 proteins: an in silico and in vitro study

B Kar, CN Kundu, MK Singh, B Dehury… - Journal of …, 2024 - Taylor & Francis
Extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae infection is a
serious global threat. ESBLs target 3rd generation cephalosporin antibiotics, the most …

In-silico screening of Acacia pennata and Bridelia retusa reveals pinocembrin-7-O-β-D-glucopyranoside as a promising β-lactamase inhibitor to combat antibiotic …

AK Umar, D Roy, M Abdalla, Y Modafer… - Journal of …, 2023 - Taylor & Francis
The β-lactamase of Pseudomonas aeruginosa is known to degrade β-lactam antibiotics
such as penicillins, cephalosporins, monobactams, and carbapenems. With the discovery of …