[HTML][HTML] Hyperhomocysteinemia and neurologic disorders: a review

R Ansari, A Mahta, E Mallack… - Journal of clinical …, 2014 - synapse.koreamed.org
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. It has a physiologic role in DNA metabolism via methylation, a process …

[HTML][HTML] The controversial role of homocysteine in neurology: from labs to clinical practice

R Moretti, P Caruso - International journal of molecular sciences, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid that is generated during methionine
metabolism. Physiologic Hcy levels are determined primarily by dietary intake and vitamin …

Hyperhomocysteinemia: clinical insights

F Al Mutairi - Journal of central nervous system disease, 2020 - journals.sagepub.com
Homocysteine (Hcy) is a sulfhydryl-containing amino acid, and intermediate metabolite
formed in metabolising methionine (Met) to cysteine (Cys); defective Met metabolism can …

[HTML][HTML] Involvements of hyperhomocysteinemia in neurological disorders

M Cordaro, R Siracusa, R Fusco, S Cuzzocrea… - Metabolites, 2021 - mdpi.com
Homocysteine (HCY), a physiological amino acid formed when proteins break down, leads
to a pathological condition called hyperhomocysteinemia (HHCY), when it is over a definite …

Homocysteine and cerebral ischemia: pathogenic and therapeutical implications

A Pezzini, E Del Zotto… - Current medicinal …, 2007 - ingentaconnect.com
Homocysteine is a thiol aminoacid synthesized during the metabolism of methionine.
Increased plasma levels of homocysteine can be the result of mutations in the enzymes …

Homocysteine and neurologic disease

R Diaz-Arrastia - Archives of neurology, 2000 - jamanetwork.com
Over the last 10 years, there has been an explosion of interest in homocysteine, a sulfur-
containing amino acid that occupies a central location in the metabolic pathways of thiol …

[HTML][HTML] Homocysteine in neurology: a possible contributing factor to small vessel disease

R Moretti, M Giuffre, P Caruso, S Gazzin… - International Journal of …, 2021 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing amino acid generated during methionine
metabolism, accumulation of which may be caused by genetic defects or the deficit of …

Hyperhomocysteinemia: impact on neurodegenerative diseases

M Sharma, M Tiwari, RK Tiwari - Basic & clinical pharmacology …, 2015 - Wiley Online Library
Neurodegenerative diseases are the diseases of the central nervous system with various
aetiology and symptoms. Dementia, Alzheimer's disease (AD), Parkinson's disease (PD) …

The central nervous system in animal models of hyperhomocysteinemia

AM Troen - Progress in Neuro-Psychopharmacology and …, 2005 - Elsevier
Growing epidemiological evidence of associations between mildly elevated plasma
homocysteine with age-related cognitive impairment, neurodegenerative and …

Homocysteine and brain atrophy

PS Sachdev - Progress in Neuro-Psychopharmacology and …, 2005 - Elsevier
Homocysteine (Hcy) has been implicated as a risk factor for vascular disease as well as
brain atrophy. There is evidence to implicate Hcy in increased oxidative stress, DNA …