Inflammasomes are intracellular multiprotein complexes in the cytoplasm that regulate
inflammation activation in the innate immune system in response to pathogens and to host …

Inflammasomes are important modulators of inflammation. Dysregulation of inflammasomes
can enhance vulnerability to conditions such as neurodegenerative diseases …

The NLRP3 inflammasome is a multimeric protein complex that initiates an inflammatory
form of cell death and triggers the release of proinflammatory cytokines IL-1β and IL-18. The …

The inflammasome is a molecular platform formed by activation of an innate immune pattern
recognition receptor seed, such as NLRP3. Once activated, NLRP3 recruits the adapter ASC …

In an ageing society, neurodegenerative diseases have attracted attention because of their
high incidence worldwide. Despite extensive research, there is a lack of conclusive insights …

The NLRP3 inflammasome is a critical component of the innate immune system that
mediates caspase-1 activation and the secretion of proinflammatory cytokines IL-1β/IL-18 in …

The prevalence of neurodegenerative disease has increased significantly in recent years,
and with a rapidly aging global population, this trend is expected to continue. These …

Inflammasomes are multiprotein complexes that trigger the activation of caspases‐1 and
subsequently the maturation of proinflammatory cytokines interleukin‐1β and interleukin‐18 …

Inflammasomes are multiprotein complexes that critically control different aspects of innate
and adaptive immunity. Among them we could highlight the release of pro-inflammatory …

Inflammasomes are multiprotein signaling platforms in the cytosol that senses exogenous
and endogenous danger signals and respond with the maturation and secretion of IL-1β and …