Assessing brain metabolism with 7-T proton magnetic resonance spectroscopy in patients with first-episode psychosis
AM Wang, S Pradhan, JM Coughlin, A Trivedi… - JAMA …, 2019 - jamanetwork.com
Importance The use of high-field magnetic resonance spectroscopy (MRS) in multiple brain
regions of a large population of human participants facilitates in vivo study of localized or …
regions of a large population of human participants facilitates in vivo study of localized or …
Proton magnetic resonance spectroscopy in first episode psychosis and ultra high-risk individuals
The underlying neurobiology of emerging psychotic disorders is not well understood. Recent
neuroimaging findings have suggested that some brain areas are affected prior to the onset …
neuroimaging findings have suggested that some brain areas are affected prior to the onset …
Brain metabolite alterations in young adults at familial high risk for schizophrenia using proton magnetic resonance spectroscopy
Background Proton magnetic resonance spectroscopy (1 H MRS) enables in-vivo
measurement of several relevant brain metabolites and has provided evidence of a range of …
measurement of several relevant brain metabolites and has provided evidence of a range of …
The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy …
Background The pathophysiology of psychosis is incompletely understood. Disruption in
cortical glutamatergic signalling causing aberrant striatal dopamine synthesis capacity is a …
cortical glutamatergic signalling causing aberrant striatal dopamine synthesis capacity is a …
In vivo evidence for cerebral bioenergetic abnormalities in schizophrenia measured using 31P magnetization transfer spectroscopy
F Du, AJ Cooper, T Thida, S Sehovic, SE Lukas… - JAMA …, 2014 - jamanetwork.com
Importance Abnormalities in neural activity and cerebral bioenergetics have been observed
in schizophrenia (SZ). Further defining energy metabolism anomalies would provide crucial …
in schizophrenia (SZ). Further defining energy metabolism anomalies would provide crucial …
Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia
Background The identification of schizophrenia biomarkers is a crucial step towards
improving current diagnosis, developing new presymptomatic treatments, identifying high …
improving current diagnosis, developing new presymptomatic treatments, identifying high …
A test of the transdiagnostic dopamine hypothesis of psychosis using positron emission tomographic imaging in bipolar affective disorder and schizophrenia
Importance The dopamine hypothesis suggests that dopamine abnormalities underlie
psychosis, irrespective of diagnosis, implicating dopamine dysregulation in bipolar affective …
psychosis, irrespective of diagnosis, implicating dopamine dysregulation in bipolar affective …
Measurement of brain metabolites by 1H magnetic resonance spectroscopy in patients with schizophrenia: a systematic review and meta-analysis
RG Steen, RM Hamer, JA Lieberman - Neuropsychopharmacology, 2005 - nature.com
A systematic review of the literature identified 64 published English-language papers that
used proton (1 H) magnetic resonance spectroscopy to measure N-acetylaspartate (NAA) …
used proton (1 H) magnetic resonance spectroscopy to measure N-acetylaspartate (NAA) …
Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega …
Importance Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …
Metabolic alterations associated with schizophrenia: a critical evaluation of proton magnetic resonance spectroscopy studies
A Schwerk, FDS Alves, PJW Pouwels… - Journal of …, 2014 - Wiley Online Library
By reviewing the existing 1H‐magnetic resonance spectroscopy literature in schizophrenia,
the relationship of different sample characteristics and applied methodologies with …
the relationship of different sample characteristics and applied methodologies with …