Adiponectin is an abundant plasma protein secreted from adipocytes that elicits protective
effects in the vasculature and myocardium. In obesity and insulin-resistant states …

Obesity is strongly associated with the pathogenesis of type 2 diabetes, hypertension, and
cardiovascular disease. Levels of the hormone adiponectin are downregulated in obese …

Adiponectin, a novel hormone made by fat tissue, regulates energy metabolism and
endothelial activation. Serum levels of adiponectin are reduced in conditions that are …

Adiponectin is a protein secreted specifically by adipose cells that may couple regulation of
insulin sensitivity with energy metabolism and serve to link obesity with insulin resistance …

Obesity is strongly associated with metabolic and cardiovascular disorders. Adiponectin is
an adipose-derived plasma protein that is downregulated in subjects with obesity-related …

The cardiometabolic syndrome, associated with increased cardiovascular disease risk in the
industrialized world, is estimated to affect one in four adults. Although the mechanisms …

The global epidemic of obesity is accompanied by an increased prevalence of
cardiovascular disease (CVD), in particular stroke and heart attack. Dysfunctional adipose …

Cardiovascular disease accounts for an overwhelming proportion of the morbidity and
mortality suffered by patients with obesity and type 2 diabetes mellitus, and recent work has …

Adiponectin is a major adipocyte-secreted adipokine abundantly present in the circulation
as three distinct oligomeric complexes. In addition to its role as an insulin sensitizer …

Objective—Adiponectin is an adipocyte-derived, secreted protein that is implicated in
protection against a cluster of related metabolic disorders. Mice lacking adiponectin display …