It is becoming increasingly clear that inflammation influences prostate cancer (PCa)
development and that immune cells are among the primary drivers of this effect. This …

Prostate cancer tissue is composed of both cancer cells and host cells. The milieu of host
components that compose the tumor is termed the tumor microenvironment (TME). Host cells …

One in seven men in North America is expected to be diagnosed with prostate cancer (PCa)
during their lifetime (,). While a wide range of treatment options including surgery, radiation …

Background Advanced prostate cancer remains one of the most common and deadly
cancers, despite advances in treatment options. Immunotherapy has provided little benefit to …

Immunotherapeutic treatment approaches are now an integral part of the treatment of many
solid tumors. However, attempts to integrate immunotherapy into the treatment of prostate …

Abstract Purpose Prostate cancer (PCa) is the most common malignancy in men and the
cause for the second most common cancer-related death in the western world. Despite …

Prostate cancer is the most commonly diagnosed cancer and the second leading cause of
cancer-related death among men in western countries. Androgen deprivation therapy (ADT) …

Introduction Prostate cancer is the most common non-cutaneous malignancy diagnosed in
men. Moving from histological observations since a long time, it has been recognized that …

Abstract In the United States and in “Westernized” countries, the prevalence of both prostate
cancer and prostate inflammation is very high, indicating that the two pathologies could be …

The heterogeneity of the immune microenvironment leads to different responses in immune
checkpoint blockade therapy. We aimed to propose a robust molecular classification system …