Detection of glutamate, glutamine, and glutathione by radiofrequency suppression and echo time optimization at 7 tesla

L An, S Li, JB Murdoch, MF Araneta… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To achieve detection of glutamate (Glu), glutamine (Gln), and glutathione (GSH) by
minimizing the N‐acetyl‐aspartate (NAA) multiplet signals at 2.49 ppm using a echo time …

Detection of glucose in the human brain with 1H MRS at 7 Tesla

LG Kaiser, K Hirokazu, M Fukunaga… - Magnetic Resonance …, 2016 - Wiley Online Library
Purpose A new method is proposed for noninvasive detection of glucose in vivo using
proton MR spectroscopy at 7 Tesla. Theory and Methods The proposed method utilizes J …

Reliability of 7T 1H‐MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence …

N Lally, L An, D Banerjee, MJ Niciu… - Journal of magnetic …, 2016 - Wiley Online Library
Purpose To ascertain the mechanisms of neuropsychiatric illnesses and their treatment,
accurate and reliable imaging techniques are required; proton magnetic resonance …

Spectral simplification for resolved glutamate and glutamine measurement using a standard STEAM sequence with optimized timing parameters at 3, 4, 4.7, 7, and 9.4 …

S Yang, J Hu, Z Kou, Y Yang - Magnetic Resonance in …, 2008 - Wiley Online Library
The C4 multiplet proton resonances of glutamate (Glu) around 2.35 ppm and glutamine
(Gln) around 2.45 ppm usually overlap in MR spectra, particularly at low‐and mid‐field …

Quantification of glutamate and glutamine using constant‐time point‐resolved spectroscopy at 3 T

M Gu, NM Zahr, DM Spielman, EV Sullivan… - NMR in …, 2013 - Wiley Online Library
Separate quantification of glutamate (Glu) and glutamine (Gln) using conventional MRS on
clinical scanners is challenging. In previous work, constant‐time point‐resolved …

N‐acetyl‐aspartyl‐glutamate detection in the human brain at 7 Tesla by echo time optimization and improved Wiener filtering

L An, S Li, ET Wood, DS Reich… - Magnetic resonance in …, 2014 - Wiley Online Library
Purpose To report enhanced signal detection for measuring N‐acetyl‐aspartyl‐glutamate
(NAAG) in the human brain at 7 Tesla by echo time (TE)‐optimized point‐resolved …

Simultaneous quantification of glutamate and glutamine by J‐modulated spectroscopy at 3 Tesla

Y Zhang, J Shen - Magnetic resonance in medicine, 2016 - Wiley Online Library
Purpose The echo time (TE) averaged spectrum is the one‐dimensional (1D) cross‐section
of the J‐resolved spectrum at J= 0. In multiecho TE‐averaged spectroscopy, glutamate (Glu) …

Selective proton‐observed, carbon‐edited (selPOCE) MRS method for measurement of glutamate and glutamine 13C‐labeling in the human frontal cortex

HM De Feyter, RI Herzog, BR Steensma… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose 13C magnetic resonance spectroscopy (MRS) in combination with infusion of 13C‐
labeled substrates has led to unique insights into human brain metabolism and …

Optimized glutamate detection at 3T

I Hancu - Journal of Magnetic Resonance Imaging: An Official …, 2009 - Wiley Online Library
Purpose: To identify the pulse sequence and acquisition parameters that result in the most
accurate and repeatable measurements of glutamate (Glu) concentration in the brain at 3T …

Detection of glutamate/glutamine resonances by 1H magnetic resonance spectroscopy at 0.5 tesla

RW Prost, L Mark, M Mewissen… - Magnetic resonance in …, 1997 - Wiley Online Library
Midfield proton magnetic resonance spectroscopy (MRS) provides a noninvasive method to
monitor glutamate and glutamine (Glx) levels in vivo. Experiments to detect the γ and β …