A mouse model of depression has been recently developed by exogenous corticosterone
(CORT) administration, which has shown to mimic HPA-axis induced depression-like state in …

Chronic glucocorticoid exposure is known to cause depression and metabolic disorders. It is
critical to improve abnormal metabolic status as well as depressive-like behaviors in patients …

Depression is one of the most common neuropsychiatric disorders and has been associated
with the neuroendocrine system and alterations in specific brain proteins. Resveratrol is a …

Classic antidepressant drugs are modestly effective across the population and most are
associated with intolerable side effects. Recently, numerous lines of evidence suggest that …

The effect and mechanism of resveratrol on depression‑like behavior in mice with
depression were investigated. A mouse model of depression was established by social …

Chronic stress occurs in everyday life and induces depression-like behaviors, associated
with proteins alterations and apoptosis in brain. Resveratrol is a natural polyphenol enriched …

Current evidence supports that depression is accompanied by the activation of the
inflammatory-response system, and overproduction of pro-inflammatory cytokines may play …

This study focused on exploring the antidepressant potential of resveratrol (RES) and its
possible mechanisms of action. Cell injury was induced by corticosterone (CORT) and …

Abstract Resveratrol (3, 4′, 5-trihydroxy-trans-stilbene) is a natural non-flavonoid
polyphenol antioxidant extracted from red grapes in the processing of wine. Initially it was …

Resveratrol is a natural polyphenol enriched in Polygonum cuspidatum and has diverse
biological activities. There is only limited information about the antidepressant-like effect of …