Are aquaporins the missing transmembrane osmosensors?

AE Hill, Y Shachar-Hill - The Journal of membrane biology, 2015 - Springer
Regulation of cell volume is central to homeostasis. It is assumed to begin with the detection
of a change in water potential across the bounding membrane, but it is not clear how this is …

What are aquaporins for?

AE Hill, B Shachar-Hill, Y Shachar-Hill - The Journal of membrane biology, 2004 - Springer
The prime function of aquaporins (AQPs) is generally believed to be that of increasing water
flow rates across membranes by raising their osmotic or hydraulic permeability. In addition …

Aquaporins at a glance

AS Verkman - Journal of cell science, 2011 - journals.biologists.com
Cell Science at a Glance 2107 enhanced osmotic compared with diffusional water
permeability, which suggested water movement through a pore-like pathway. The molecular …

[图书][B] Aquaporins

B Yang - 2017 - Springer
The mechanisms and physiological functions of water transport across biological
membranes are subjects of long-standing interest. Recent advances in the molecular …

AQPs and control of vesicle volume in secretory cells

H Sugiya, M Matsuki - The Journal of membrane biology, 2006 - Springer
Aquaporins (AQPs) are a family of small, hydrophobic, integral membrane proteins. In
mammals, they are expressed in many epithelia and endothelia and function as channels …

[HTML][HTML] Aquaporin-1, nothing but a water channel

SP Tsunoda, B Wiesner, D Lorenz, W Rosenthal… - Journal of Biological …, 2004 - ASBMB
Aquaporin-1 (AQP1) is a membrane channel that allows rapid water movement driven by a
transmembrane osmotic gradient. It was claimed to have a secondary function as a cyclic …

Novel roles for aquaporins as gated ion channels

AJ Yool, WD Stamer - Advances in Molecular and Cell Biology, 2004 - Elsevier
Publisher Summary This chapter focuses on the novel roles played by aquaporins (AQPs)
as gated ion channels. AQPs are the members of the major intrinsic protein (MIP) gene …

Membrane trafficking of aquaporin 1 is mediated by protein kinase C via microtubules and regulated by tonicity

MT Conner, AC Conner, JEP Brown, RM Bill - Biochemistry, 2010 - ACS Publications
It is well-known that the rapid flow of water into and out of cells is controlled by membrane
proteins called aquaporins (AQPs). However, the mechanisms that allow cells to quickly …

[HTML][HTML] Aquaporins: another piece in the osmotic puzzle

K Alleva, O Chara, G Amodeo - FEBS letters, 2012 - Elsevier
Osmolarity not only plays a key role in cellular homeostasis but also challenges cell survival.
The molecular understanding of osmosis has not yet been completely achieved, and the …

Beyond water homeostasis: Diverse functional roles of mammalian aquaporins

P Kitchen, RE Day, MM Salman, MT Conner… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Background Aquaporin (AQP) water channels are best known as passive transporters of
water that are vital for water homeostasis. Scope of review AQP knockout studies in whole …