Biofilm formation by Streptococcus mutans is considered as its principal virulence factor,
causing dental caries. Mutants of S. mutans defective in biofilm formation were generated …

Streptococcus mutans, an oral pathogen associated with dental caries, colonizes tooth
surfaces as polymicrobial biofilms known as dental plaque. S. mutans expresses several …

ABSTRACT Group A Streptococcus (GAS) commonly infects the human oropharynx, but the
initial molecular events governing this process are poorly understood. Saliva is a major …

Studies were initiated to investigate the regulation of Streptococcus mutans genes which are
believed to be important to virulence. Operon fusions were constructed between S. mutans …

Streptococcus mutans, the primary etiological agent of human dental caries, is an obligate
biofilm-forming bacterium. The goals of this study were to identify the gene (s) required for …

Introduction: Dental caries has been closely linked to fermentable carbohydrates as key
environmental factors. Sucrose has been identified as the most cariogenic carbohydrate …

Oral Diseases (2012) 18, 485–493 Objective: Streptococcus mutans are members of the oral
microbiota that are implicated in dental caries and infective endocarditis. To adapt to …

The cariogenic pathogen Streptococcus mutans effectively utilizes dietary sucrose for the
synthesis of exopolysaccharide, which act as a scaffold for its biofilm, thus contributing to its …

Streptococcus mutans, a major etiological agent of human dental caries, produces
membrane vesicles (MVs) that contain protein and extracellular DNA. In this study, functional …

Streptococcus mutans is a biofilm-forming bacterium that is adapted to tolerate rapid and
dramatic fluctuations in nutrient availability, carbohydrate source, and pH in its natural …