The role of IL-33/ST2L signals in the immune cells
J Lu, J Kang, C Zhang, X Zhang - Immunology letters, 2015 - Elsevier
Abstract Interleukin (IL)-33 signals influence various immune cells during differentiation,
immune responses and homeostasis. As discussed in this Review, IL-33 via TI/ST2L …
immune responses and homeostasis. As discussed in this Review, IL-33 via TI/ST2L …
[HTML][HTML] Pleiotropic Effects of IL-33 on CD4+ T Cell Differentiation and Effector Functions
F Alvarez, JH Fritz, CA Piccirillo - Frontiers in immunology, 2019 - frontiersin.org
IL-33, a member of the IL-1 family of cytokines, was originally described in 2005 as a
promoter of type 2 immune responses. However, recent evidence reveals a more complex …
promoter of type 2 immune responses. However, recent evidence reveals a more complex …
The IL-33/ST2 axis: role in health and disease
Abstract IL-33, an IL-1 family member, is expressed by many cell types and can regulate
gene transcription. IL-33 is released upon cell necrosis and the precursor form is …
gene transcription. IL-33 is released upon cell necrosis and the precursor form is …
[HTML][HTML] Signaling and functions of interleukin-33 in immune regulation and diseases
XM Yi, H Lian, S Li - Cell Insight, 2022 - Elsevier
Abstract Interleukin-33 (IL-33) which belongs to the interleukin-1 (IL-1) family is an alarmin
cytokine with critical roles in tissue homeostasis, pathogenic infection, inflammation, allergy …
cytokine with critical roles in tissue homeostasis, pathogenic infection, inflammation, allergy …
IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells
MD Smithgall, MR Comeau… - International …, 2008 - academic.oup.com
Abstract IL-33 is an IL-1 family member recently identified as the ligand for T1/ST2 (ST2), a
member of the IL-1 receptor family. ST2 is stably expressed on mast cells and Th2 effector T …
member of the IL-1 receptor family. ST2 is stably expressed on mast cells and Th2 effector T …
The role of the IL-33/ST2 axis in autoimmune disorders: friend or foe?
X Liu, Y Xiao, Y Pan, H Li, SG Zheng, W Su - Cytokine & growth factor …, 2019 - Elsevier
Autoimmune diseases (ADs), which are common immune-mediated inflammatory
syndromes, are characterized by an imbalance between T effector (Th) 1/Th17 cells and T …
syndromes, are characterized by an imbalance between T effector (Th) 1/Th17 cells and T …
IL-33/ST2 axis in autoimmune disease
L Shakerian, H Kolahdooz, M Garousi, V Keyvani… - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33) is a member of the IL-1 family and plays an ambivalent role in
autoimmune diseases. IL-33 signals via the ST2 receptor and drives cytokine production in …
autoimmune diseases. IL-33 signals via the ST2 receptor and drives cytokine production in …
IL-33: a potential therapeutic target in autoimmune diseases
S Wang, L Ding, SS Liu, C Wang… - Journal of …, 2012 - journals.sagepub.com
Interleukin 33 (IL-33) is a newly described member of the IL-1 superfamily of cytokines.
Through activation of the ST2 receptor, which is widely expressed particularly by helper T 2 …
Through activation of the ST2 receptor, which is widely expressed particularly by helper T 2 …
IL-33/ST2 axis in inflammation and immunopathology
M Milovanovic, V Volarevic, G Radosavljevic… - Immunologic …, 2012 - Springer
Abstract Interleukin-33 (IL-33), a member of the IL-1 family of cytokines, binds to its plasma
membrane receptor, heterodimeric complex consisted of membrane-bound ST2L and IL-1R …
membrane receptor, heterodimeric complex consisted of membrane-bound ST2L and IL-1R …
Interleukin-33 in health and disease
FY Liew, JP Girard, HR Turnquist - Nature Reviews Immunology, 2016 - nature.com
Abstract Interleukin-33 (IL-33)—a member of the IL-1 family—was originally described as an
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …
inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now …