Bioactive compounds from sour orange inhibit colon cancer cell proliferation and induce cell cycle arrest
GK Jayaprakasha, Y Jadegoud… - Journal of agricultural …, 2010 - ACS Publications
Epidemiological studies suggest that dietary limonoids and phytosterols offer protection from
certain types of cancers. Potential cancer preventive constituents of sour orange (Citrus …
certain types of cancers. Potential cancer preventive constituents of sour orange (Citrus …
Novel triterpenoid from Citrus aurantium L. possesses chemopreventive properties against human colon cancer cells
Potential cancer preventive constituents of sour orange (Citrus aurantium L.) were isolated
and identified from EtOAc extract of sour orange. Crude EtOAc extract was purified using …
and identified from EtOAc extract of sour orange. Crude EtOAc extract was purified using …
Citrus monoterpenes: potential source of phytochemicals for cancer prevention
KN Chidambara Murthy, GK Jayaprakasha… - Emerging trends in …, 2012 - ACS Publications
Dietary monoterpenes are non-nutritive volatile principles found in citrus and other regularly
consumed plant constituents. Monoterpenes are gaining significant importance as major …
consumed plant constituents. Monoterpenes are gaining significant importance as major …
Cancer chemopreventive properties of citrus limonoids
Limonoids constitute one of the major phytochemicals along with flavonoids, coumarins, and
carotenoids in citrus. Limonoids were shown to possess cancer preventive properties. In the …
carotenoids in citrus. Limonoids were shown to possess cancer preventive properties. In the …
Citrus limonin and its glucoside inhibit colon adenocarcinoma cell proliferation through apoptosis
KN Chidambara Murthy, GK Jayaprakasha… - Journal of agricultural …, 2011 - ACS Publications
The current study was an attempt to elucidate the mechanism of human colon cancer cell
proliferation inhibition by limonin and limonin glucoside (LG) isolated from seeds of Citrus …
proliferation inhibition by limonin and limonin glucoside (LG) isolated from seeds of Citrus …
Antiproliferative activities of citrus flavonoids against six human cancer cell lines
JA Manthey, N Guthrie - Journal of Agricultural and Food …, 2002 - ACS Publications
Citrus fruits contain high concentrations of several classes of phenols, including numerous
hydroxycinnamates, flavonoid glycosides, and polymethoxylated flavones. The latter group …
hydroxycinnamates, flavonoid glycosides, and polymethoxylated flavones. The latter group …
Differential inhibition of human colon cancer cells by structurally similar flavonoids of citrus
A number of studies in the recent years have evaluated the anti-proliferative activity of
flavonoids. Although certain studies investigated the structure–activity based on the …
flavonoids. Although certain studies investigated the structure–activity based on the …
Differential inhibition of human cancer cell proliferation by citrus limonoids
Limonoids have been shown to inhibit the growth of estrogen receptor-negative and-positive
human breast cancer cells in culture. The primary objective of this study was to test the …
human breast cancer cells in culture. The primary objective of this study was to test the …
Antiproliferative effects of citrus limonoids against human neuroblastoma and colonic adenocarcinoma cells
SM Poulose, ED Harris, BS Patil - Nutrition and cancer, 2006 - Taylor & Francis
Limonoids, a family of triterpenoids with putative anticancer properties, occur in fruits as
glucosides and aglycones. Both highly purified forms were isolated from seeds and …
glucosides and aglycones. Both highly purified forms were isolated from seeds and …
5-Geranyloxy-7-methoxycoumarin inhibits colon cancer (SW480) cells growth by inducing apoptosis
For the first time, three coumarins were isolated from the hexane extract of limes (Citrus
aurantifolia) and purified by flash chromatography. The structures were identified by NMR …
aurantifolia) and purified by flash chromatography. The structures were identified by NMR …