We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes
(T2D) in east Asian populations. We followed our stage 1 meta-analysis of eight T2D …

Twin and family studies have demonstrated a strong genetic component to type 2 diabetes
mellitus (T2DM), but mapping the susceptibility genes that account for this risk has proved …

OBJECTIVE Recent genome-wide association studies have resulted in a dramatic increase
in our knowledge of the genetic loci involved in type 2 diabetes. In a complementary …

Background Type 2 diabetes (T2D) is a heterogeneous disease for which (1) disease-
causing pathways are incompletely understood and (2) subclassification may improve …

Type 2 diabetes mellitus is a heterogeneous inherited disorder characterized by chronic
hyperglycemia resulting from pancreatic β-cell dysfunction and insulin resistance. Although …

Susceptibility to type 1 diabetes (T1D) is determined by complex interactions between
several genetic loci and environmental factors. Alleles at the human leukocyte antigen (HLA) …

To understand the genetics of type 2 diabetes in people of Japanese ancestry, we
conducted A meta-analysis of four genome-wide association studies (GWAS; 36,614 cases …

Abstract Knowledge of the genetics of type 2 diabetes mellitus (T2DM) has evolved
tremendously over the past few years. Following advances in technology and analytical …

We conducted a genome-wide association study of type 2 diabetes (T2D) using 459,359
SNPs in a Japanese population with a three-stage study design (stage 1, 4,470 cases and …

OBJECTIVE—This study examined how differences in the BMI distribution of type 2 diabetic
case subjects affected genome-wide patterns of type 2 diabetes association and considered …