Importance of mixed chimerism to predict relapse in persistently BCR/ABL positive long survivors after allogeneic bone marrow transplantation for chronic myeloid …

J Roman, C Martin, A Torres, A Garcia… - Leukemia & …, 1998 - Taylor & Francis
Determination of hematological chimerism could be helpful in understanding the biology of
leukemic relapse after allogeneic bone marrow transplant (BMT) for chronic myeloid …

Myeloid mixed chimerism is associated with relapse in bcr-abl positive patients after unmanipulated allogeneic bone marrow transplantation for chronic myelogenous …

J Román, J Serrano, A Jiménez, JA Castillejo… - …, 2000 - haematologica.org
BACKGROUND AND OBJECTIVE: Although bcr-abl polymerase chain reaction (PCR)
positivity after bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML) …

Molecular analysis of lineage-specific chimerism and minimal residual disease by RT-PCR of p210BCR-ABL and p190BCR-ABL after allogeneic bone marrow transplantation …

J Serrano, J Roman, J Sanchez… - Blood, The Journal …, 2000 - ashpublications.org
We studied lineage-specific chimerism and minimal residual disease (MRD) in sequential
posttransplant samples from 55 patients who underwent unmanipulated (n= 44) or partially T …

Donor chimaerism is a strong indicator of disease free survival following bone marrow transplantation for chronic myeloid leukaemia.

N GARDINER, M LAWLER… - Leukemia …, 1997 - search.ebscohost.com
Abstract Although Chronic Myeloid Leukaemia (CML) can be treated successfully with
allogeneic bone marrow transplantation (BMT), leukaemia relapse remains a significant …

Prediction and reversion of post-transplant relapse in patients with chronic myeloid leukemia using mixed chimerism and residual disease detection and adoptive …

R Formánková, L Honzátková, J Moravcová… - Leukemia research, 2000 - Elsevier
In the prospective study, we examined hematopoietic mixed chimerism (using polymerase
chain reaction (PCR) of variable number of tandem repeat-VNTR sequences) and minimal …

A comparison of chimerism and minimal residual disease between four different allogeneic transplantation methods in patients with chronic myelogenous leukemia in …

AH Elmaagacli, K Runkel, N Steckel, B Opalka… - Bone marrow …, 2001 - nature.com
The detection of chimerism, residual molecular and cytogenetic disease following
transplantation of peripheral blood stem cells (PBSCT) with a nonmyeloablative conditioning …

Persistent donor chimaerism is consistent with disease-free survival following BMT for chronic myeloid leukaemia

N Gardiner, M Lawler, J O'Riordan, M DeArce… - Bone marrow …, 1997 - nature.com
Chronic myeloid leukaemia (CML) can be treated successfully with allogeneic bone marrow
transplantation (BMT) leading to long-term disease-free survival. Leukemia relapse …

Minimal residual disease is more common in patients who have mixed T-cell chimerism after bone marrow transplantation for chronic myelogenous leukemia

S Mackinnon, L Barnett, G Heller, RJ O'Reilly - 1994 - ashpublications.org
Determining both lymphoid chimerism and the presence of minimal residual disease after
allogeneic bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML) …

Sequential molecular monitoring of chimerism in chronic myeloid leukemia patients receiving donor lymphocyte transfusion for relapse after bone marrow …

MC Rapanotti, W Arcese, S Buffolino, AP Iori… - Bone marrow …, 1997 - nature.com
Recent observations of chimerism in patients relapsed following an allotransplant suggest
the persistence of immunotolerance, thus offering a biologic rationale for the use of donor …

Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in …

JP Radich, G Gehly, T Gooley, E Bryant, RA Clift… - 1995 - ashpublications.org
We studied 346 patients after bone marrow transplantation (BMT) for chronic myeloid
leukemia (CML) for the presence of the bcr-abl transcript detected by the polymerase chain …